ALZHEIMER'S

Aging is the process of becoming older. The term refers mainly to humans, many other animals, and fungi, whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. In a broader sense, ageing can refer to single cells within an organism which have ceased dividing, or to the population of a species. In humans, ageing represents the accumulation of changes in a human being over time and can encompass physical, psychological, and social changes. Reaction time, for example & memories may slow with age, while general knowledge typically increase. Ageing is associated with increased risk of cancer, Alzheimer's disease, diabetes, cardiovascular disease, increased mental health risks, and many more. Of the roughly 150,000 people who die each day across the globe, about two-thirds die from age-related causes. Certain lifestyle choices and socioeconomic conditions been linked to ageing. Current ageing theories are assigned to the damage concept, whereby the accumulation of damage (such as DNA oxidation) may cause biological systems to fail, or to the programmed ageing concept, whereby the internal processes (epigenetic maintenance such as DNA methylation) inherently may cause ageing. Programmed ageing should not be confused with programmed cell death (apoptosis). in heaven Christians and jews are young again even though they died old ;it is written in the Holy Bible the word of the Lord according to prophet it is written in the Holy King James Bible the word of the Lord according to saint isaiah the prophet 700 BC Before Christ Isaiah 40:31 But they that wait upon the LORD shall renew their strength; they shall mount up with wings as eagles; they shall run & not be weary; & they shall walk & not faint. amen Hallelujah Hallelujah Blessed be the word of the Lord for Christ is risen Hallelujah Hallelujah  peace be still in Nomine Patris et FiLii et Spiritus Sancti amen
https://www.youtube.com/watch?v=_fGEnQcke04
2016 Roy Walford lecture NAD, Sirtuins and Aging
https://www.youtube.com/watch?v=aOW_HslF5ko
THIS Is The Fastest Way To Get Dementia… | The Brain Doctor, Dr Ann Mckee
https://www.youtube.com/watch?v=xHlNXzfCv0o
The Biology of Aging
https://www.youtube.com/watch?v=MPXgNCefknI
The Art of Aging Well
https://www.youtube.com/watch?v=woHUjZzyG8M
Cynthia Kenyon | Genes and cells that influence the rate of aging | Frontiers Forum Live 2023

Alzheimer's disease is a neurodegenerative disease that usually starts slowly and progressively worsens, & is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, & behavioral issues. As a person's condition declines, they often withdraw from family & society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the average life expectancy following diagnosis is three to twelve years. Amyloid plaques build up in Alzheimer's brains . Obesity increases 3x the risk of Alzheimer's Plaques form when protein pieces called beta-amyloid clump together. Beta-amyloid comes from a larger protein found in the fatty membrane surrounding nerve cells. Beta-amyloid is chemically "sticky" and gradually builds up into plaques. Beta amyloids comes from LDH cholesterol Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid-beta precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ in a cholesterol-dependent process and substrate presentation. Beta-amyloid comes from a larger protein found in the fatty membrane surrounding nerve cells. Beta-amyloid is chemically "sticky" and gradually builds up into plaques. The brain shrinks with age due to a lack of HDL high density lipo protein omega 3 Although a unified theory for microbial colonization of the brain has not been formed, multiple research groups have suggested ways this occurs. Weber et al noted that specific species of bacteria identified in studies exploring the brain microbiome in AD are normally found in the oral microbiome. Therefore, they hypothesized, that pathogenic changes in the oral cavity (often seen in AD) may damage connective tissues. This tissue destruction releases bacteria from the oral cavity, allowing for nervous system infection. Some of these bacteria can create a biofilm, through the production of amyloid proteins. These bacterial amyloids share similarities to the disease-causing versions.13 These amyloids may then allow other native amyloid proteins to aggregate and form colonies, beginning the pathogenesis of AD. Silica removes plaque deposits on nerve endings Aluminum out of the brain allowing for quick clear brain signals. to prevent Alzheimer's ingest charcoal smoothies and own a hydrogen water bottle turns out fatty acids what the brain is made of are composed of carbon & Hydrogen the lack of minerals & carbon in the skull cause the skulls to thin with cavities to avoid this supplement with charcoal smoothies for carbon & drink gastroliths. Etanercept, the active ingredient used in perispinal administration (commonly branded as Enbrel), is a large, complex dimeric fusion protein with the chemical formula : C2224H3475N621O698S36.  Key Structural & Formulation Detail: Structure: It is a dimeric, fully human soluble TNF receptor Fc fusion protein, consisting of 934 amino acids with a molecular weight of approximately 150 kilodaltons (kDa).Composition: Perispinal etanercept combine the extracellular ligand-binding portion of the human 75 kDa (p75) TNF receptor with the Fc portion of human IgG1. Perispinal Formulation: For perispinal administration, etanercept is typically prepared by solubilizing the lyophilized powder (25 mg vial) with 1.8 cc of sterile water, which often includes sucrose, sodium chloride, L-arginine hydrochloride, and sodium phosphate. Mechanism: Perispinal etanercept acts as a tumor necrosis factor (TNF) inhibitor, used in studies for neuroinflammation. Perispinal etanercept has miraculous heling effect on Alzheimer's patients . 2 A second drug called Kisunla (donanemab) a complex monoclonal antibody protein, not a simple compound with a single chemical formula like water; its formula is approximately C6452H10038N1708O2013S42, representing its large peptide structure with sugars, with a molecular weight around 145 kDa, used to treat early Alzheimer's by targeting amyloid plaques. Lithium shows promise for Alzheimer's prevention and treatment, with studies suggesting naturally lower levels are linked to increased risk, while supplementation, especially with specific salts like lithium orotate, might reduce amyloid plaques, tau tangles, and cognitive decline in mice, potentially by restoring brain lithium levels depleted by plaques. While some clinical trials are exploring low-dose lithium for agitation and cognition in AD, overall meta-analyses haven't confirmed broad effectiveness yet, highlighting the need for more research on specific lithium compounds and dosing for humans . Hypoperfusion in Alzheimer's refers to the reduced blood flow (oxygen/nutrients) to the brain, a key factor contributing to cognitive decline, linking vascular issues with AD pathology, causing white matter damage, inflammation, and amyloid/tau problems, and acting as an early sign or precursor, suggesting improving blood flow might help treatment. Chronic poor perfusion stresses brain cells, leading to neurodegeneration, affecting memory and function, and is often seen with vascular risk factors so take Albumin as a supplement to improve blood flow & stop drinking sugar & eating 95% carbs switch to a ketogenic diet of 5% carbs 95% protein & may your brain . Gut microbiota dysbiosis, or an imbalance in gut bacteria, is closely linked to the onset and progression of Alzheimer’s disease (AD). This imbalance promote systemic inflammation, disrupt the blood-brain barrier & accelerate the accumulation of amyloid-beta (Aβ) plaques and tau tangles via the gut-brain axis. Key Connection Between Dysbiosis and Alzheimer's Microbial Imbalance: AD patients often show a decrease in beneficial bacteria (e.g., Firmicutes, Bifidobacteria) and an increase in pro-inflammatory bacteria (e.g., Bacteroidetes, Proteobacteria). Neuroinflammation: Reduced level of protective, short-chain fatty acids (SCFAs) like butyrate, alongside increased bacterial toxins (lipopolysaccharides, or LPS), lead to chronic inflammation that damage neurons. Blood-Brain Barrier (BBB) Dysfunction: Dysbiosis increase intestinal permeability, allowing bacteria-derived products to enter the bloodstream and enter the brain, promoting neuroinflammation. The APOE4 Link: Carriers of the APOE4 gene, the strongest genetic risk factor for Alzheimer's, exhibit a distinct, more pro-inflammatory gut microbiome, even before cognitive decline. Potential Therapeutic Strategy

Probiotics/Prebiotics: Introducing beneficial bacteria (e.g., Lactobacillus, Bifidobacterium) can improve cognitive function and reduce amyloid-beta in animal models. Dietary Adjustment: Diet play a major role in shaping the microbiome and can be used to mitigate inflammation. Fecal Microbiota Transplantation (FMT): Modifying the microbiome via transplantation as last resort is being investigated to reverse dysbiosis. Disclaimer: While study in mice and early human trial show promise, therapeutic intervention targeting the microbiome for Alzheimer's are still under investigation don't drink sugar nor eat a high carb diet be on a low arb diet and drink cement heavy water be blessed by God the Father God the Son & God the Holy Spirit Hallelujah Hallelujah Blessed be the word of the Lord for Christ is risen Hallelujah Hallelujah  peace be still in Nomine Patris et FiLii et Spiritus Sancti amen
https://www.youtube.com/watch?v=zTd0-A5yDZI
Inside Alzheimer’s disease
https://www.youtube.com/watch?v=YMwZIqWQl-k
Alzheimer's Disease: Latest Research and Prevention Strategies
https://www.youtube.com/watch?v=IG_iwNY3woI
Transmission of misfolded proteins in neurodegenerative disorders (Dr. Virginia Lee}
https://www.youtube.com/watch?v=BW2zN3J2lfs
ALZHEIMER'S - CAN WE PREVENT IT?
https://www.youtube.com/watch?v=k_P7Y0-wgos
The Man With The Seven Second Memory
https://www.youtube.com/watch?v=RmGqfOxgKXw
Alzheimer's Disease: A Beautiful Mind is a Horrible Thing to Waste
https://www.youtube.com/watch?v=8wAwQ6F7yWA
'Miracle' drug giving hope to Alzheimer's sufferers | 60 Minutes Australia
https://www.youtube.com/watch?v=Ow217dYc3Uw
New Alzheimer's drug approved in Australia | 7NEWS
https://www.youtube.com/watch?v=dS_cJferURA
How a Medical Mystery in Guam Led to a New Approach to Alzheimer’s Disease
https://www.youtube.com/watch?v=oXKnc3OlTXo
Alzheimer's Disease - Pathology, Tangles, Beta Amyloids
https://www.youtube.com/watch?v=bQsgiBh0QCY
Mechanism of Alzheimer's Disease

American Health Care needs to change & become a canadian health care plan Healthcare in the United States is largely provided by private sector healthcare facilities, and paid for by a combination of public programs, private insurance, and out-of-pocket payments. The U.S. is the only developed country without a system of universal healthcare, and a significant proportion of its population lacks health insurance. The United States spends more on healthcare than any other country, both in absolute terms and as a percentage of GDP; however, this expenditure does not necessarily translate into better overall health outcomes compared to other developed nations.[6] Coverage varies widely across the population, with certain groups, such as the elderly and low-income individuals, receiving more comprehensive care through government programs such as Medicaid and Medicare. The U.S. healthcare system has been the subject of significant political debate and reform efforts, particularly in the areas of healthcare costs, insurance coverage, and the quality of care. Legislation such as the Affordable Care Act of 2010 has sought to address some of these issues, though challenges remain. Uninsured rates have fluctuated over time, and disparities in access to care exist based on factors such as income, race, and geographical location. The private insurance model predominates, and employer-sponsored insurance is a common way for individuals to obtain coverage. The complex nature of the system, as well as its high costs, has led to ongoing discussions about the future of healthcare in the United States. At the same time, the United States is a global leader in medical innovation, measured either in terms of revenue or the number of new drugs and medical devices introduced. The Foundation for Research on Equal Opportunity concluded that the United States dominates science and technology, which "was on full display during the COVID-19 pandemic, as the U.S. government [delivered] coronavirus vaccines far faster than anyone had ever done before", but lags behind in fiscal sustainability, with "[government] spending ... growing at an unsustainable rate". In the early 20th century, advances in medical technology and a focus on public health contributed to a shift in healthcare. The American Medical Association (AMA) worked to standardize medical education, and the introduction of employer-sponsored insurance plans marked the beginning of the modern health insurance system. More people were starting to get involved in healthcare like state actors, other professionals/practitioners, patients and clients, the judiciary, and business interests and employers. They had interest in medical regulations of professionals to ensure that services were provided by trained and educated people to minimize harm. The post–World War II era saw a significant expansion in healthcare where more opportunities were offered to increase accessibility of services. The passage of the Hill–Burton Act in 1946 provided federal funding for hospital construction, and Medicare and Medicaid were established in 1965 to provide healthcare coverage to the elderly and low-income populations, respectively. Hallelujah Hallelujah Blessed be the word of the Lord for Christ is risen Hallelujah Hallelujah  peace be still in Nomine Patris et FiLii et Spiritus Sancti amen

Avian flu Avian influenza, also known as avian flu or bird flu, is a disease caused by the influenza A virus, which primarily affects birds but can sometimes affect mammals including humans. Wild aquatic birds are the primary host of the influenza A virus, which is enzootic (continually present) in many bird populations. Symptoms of avian influenza vary according to both the strain of virus underlying the infection, and on the species of bird or mammal affected. Classification of a virus strain as either low pathogenic avian influenza (LPAI) or high pathogenic avian influenza (HPAI) is based on the severity of symptoms in domestic chickens and does not predict severity of symptoms in other species. Chickens infected with LPAI display mild symptoms or are asymptomatic, whereas HPAI causes serious breathing difficulties, significant drop in egg production, and sudden death. Domestic poultry may potentially be protected from specific strains of the virus by vaccination. Humans and other mammals can only become infected with avian influenza after prolonged close contact with infected birds. In mammals including humans, infection with avian influenza (whether LPAI or HPAI) is rare. Symptoms of infection vary from mild to severe, including fever, diarrhoea, and cough. Influenza A virus is shed in the saliva, mucus, and feces of infected birds; other infected animals may shed bird flu viruses in respiratory secretions and other body fluids (e.g., cow milk). The virus can spread rapidly through poultry flocks and among wild birds. A particularly virulent strain, influenza A virus subtype H5N1 (A/H5N1) has the potential to decimate domesticated poultry stocks and an estimated half a billion farmed birds have been slaughtered in efforts to contain the virus Hallelujah Hallelujah Blessed be the word of the Lord for Christ is risen Hallelujah Hallelujah  peace be still in Nomine Patris et FiLii et Spiritus Sancti amen
https://www.youtube.com/watch?v=FYSnR8w9yV0
Silent Spreaders: Unmasking the Deadly Avian Influenza Virus | Documentary