THE HUMAN BODY

Tau proteins (abbreviated from tubulin associated unit) form a group of six highly soluble protein isoforms produced by alternative splicing from the gene MAPT (microtubule-associated protein tau). They have roles primarily in maintaining the stability of microtubules in axons and are abundant in the neurons of the central nervous system (CNS), where the cerebral cortex has the highest abundance. They are less common elsewhere but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. Pathologies and dementias of the nervous system such as Alzheimer's disease and Parkinson's disease are associated with tau proteins that have become hyperphosphorylated insoluble aggregates called neurofibrillary tangles. The tau proteins were identified in 1975 as heat-stable proteins essential for microtubule assembly, and since then they have been characterized as intrinsically disordered proteins. The tau hypothesis states that excessive or abnormal phosphorylation of tau results in the transformation of normal adult tau into paired-helical-filament (PHF) tau and neurofibrillary tangles (NFTs). The stage of the disease determines NFTs' phosphorylation. In AD, at least 19 amino acids are phosphorylated; pre-NFT phosphorylation occurs at serine 199, 202 and 409, while intra-NFT phosphorylation happens at serine 396 and threonine 231. Through its isoforms and phosphorylation, tau protein interacts with tubulin to stabilize microtubule assembly. All of the six tau isoforms are present in an often hyperphosphorylated state in paired helical filaments (PHFs) in the AD brain. Tau mutations have many consequences, including microtubule dysfunction and alteration of the expression level of tau isoforms. Mutations that alter function and isoform expression of tau lead to hyperphosphorylation. The process of tau aggregation in the absence of mutations is not known but might result from increased phosphorylation, protease action or exposure to polyanions, such as glycosaminoglycans. Hyperphosphorylated tau disassembles microtubules and sequesters normal tau, MAPT 1 (microtubule associated protein tau 1), MAPT 2 and ubiquitin into tangles of PHFs. This insoluble structure damages cytoplasmic functions and interferes with axonal transport, which can lead to cell death. Hyperphosphorylated forms of tau protein are the main component of PHFs of NFTs in the brain of AD patients. It has been well demonstrated that regions of tau six-residue segments, namely PHF6 (VQIVYK) and PHF6* (VQIINK), can form tau PHF aggregation in AD. Apart from the PHF6, some other residue sites like Ser285, Ser289, Ser293, Ser305 and Tyr310, located near the C-terminal of the PHF6 sequences, play key roles in the phosphorylation of tau. Hyperphosphorylated tau differs in its sensitivity and its kinase as well as alkaline phosphatase activity and is, along with beta-amyloid, a component of the pathologic lesion seen in Alzheimer disease. A recent hypothesis identifies the decrease of reelin signaling as the primary change in Alzheimer's disease that leads to the hyperphosphorylation of tau via a decrease in GSK3β inhibition. A68 is a name sometimes given (mostly in older publications) to the hyperphosphorylated form of tau protein found in the brains of individuals with Alzheimer's disease. In 2020, researchers from two groups published studies indicating that an immunoassay blood test for the p-tau-217 form of the protein could diagnose Alzheimer's up to decades before dementia symptoms were evident. Autophagy clears up misfolded tau proteins
https://www.youtube.com/watch?v=izRAjlx876Y
Tau Protein Pathology in Alzheimer's Disease
https://www.youtube.com/watch?v=vtOKJequi3A
A new perspective on the role of phosphorylation in Alzheimer’s and other tau pathologies

Telomerase are made of Nitrogen Hydrogen Oxygen & phosphorus make sure to supplement in order to increase your telomeres Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences at each end of the chromosomes of most eukaryotes. Telomeres protect the end of the chromosome from DNA damage or from fusion with neighbouring chromosomes. The fruit fly Drosophila melanogaster lacks telomerase, but instead uses retrotransposons to maintain telomeres. Telomerase is a reverse transcriptase enzyme that carries its own RNA molecule (e.g., with the sequence 3′-CCCAAUCCC-5′ in Trypanosoma brucei) which is used as a template when it elongates telomeres. Telomerase is active in gametes and most cancer cells, but is normally absent in most somatic cells. The existence of a compensatory mechanism for telomere shortening was first found by Soviet biologist Alexey Olovnikov in 1973, who also suggested the telomere hypothesis of aging and the telomere's connections to cancer and perhaps some neurodegenerative diseases. Telomerase in the ciliate Tetrahymena was discovered by Carol W. Greider and Elizabeth Blackburn in 1984. Together with Jack W. Szostak, Greider and Blackburn were awarded the 2009 Nobel Prize in Physiology or Medicine for their discovery. Later the cryo-EM structure of telomerase was first reported in T. thermophila, to be followed a few years later by the cryo-EM structure of telomerase in humans. The role of telomeres and telomerase in cell aging and cancer was established by scientists at biotechnology company Geron with the cloning of the RNA and catalytic components of human telomerase and the development of a polymerase chain reaction (PCR) based assay for telomerase activity called the TRAP assay, which surveys telomerase activity in multiple types of cancer. The negative stain electron microscopy (EM) structures of human and Tetrahymena telomerases were characterized in 2013. Two years later, the first cryo-electron microscopy (cryo-EM) structure of telomerase holoenzyme (Tetrahymena) was determined. In 2018, the structure of human telomerase was determined through cryo-EM by UC Berkeley scientists.
https://www.youtube.com/watch?v=i6nE6gUp2cw
Telomerase Function - Animation
https://www.youtube.com/watch?v=wf6QiIlGxSg
Telomerase Replication in Eukaryotes | End Replication

The brain is 2% of body mass frontal lobe, parietal lobe, temporal lobe, occipital lobe ,pons ,medulla oblongata & brainstem 1 Corinthians 2:16 For who hath known the mind of the Lord, that he may instruct him? But we have the mind of Christ.  God created the mind of man whoever is not living with God shall not have the mind of God  whoever lives without God shall be mentally insane. 40% of the brain is made of unsaturated fatty acids called omega 3 DHA makes up over 90% of the n-3 PUFAs in the brain and 10%–20% of its total lipids. DHA is especially concentrated in the gray matter DHA comprises approximately 40% of total fatty acids in the brain, while EPA comprises less than 1% of total brain acids. Approximately 50-60% of the brain weight comprises lipids, of which 35% consists of omega-3 PUFAs.The human brain weighs about 3 lbs. (1.4 kilograms) & makes up about 2% of a human's body weight. On average, male brains are about 10% larger than female brains, according to Northwestern Medicine in Illinois. The average male has a brain volume of nearly 78 cubic inches (1,274 cubic centimeters), while the average female brain has a volume of 69 cubic inches (1,131 cubic cm). The cerebrum, which is the main part of the brain located in the front area of the skull, makes up 85% of the brain's weight. The interior structure of a leech is divided into 32 different segments, each of which has its own brain. Silkworms have 11 brains​. The brain, which serves as the silkworm's primary control centre, is situated in the centre of the head. Thanks to their nine brains, it seems that octopuses have the benefit of both localized and centralized control over their actions. The human brain is made of 86 billion neurons with over 1 trillion neurons running on 20 to 24 watts of power, each neuron fires 0-50 times a second there are about 120 different type of neurons in the human brain the brain needs Copper to Form conductive pathways on the printed circuit board of the brain & Tin : Used as solder to connect components of your brain. The brain needs Gold, Silver, Palladium, Platinum: Used in connectors, pins, and other critical components of a motherboard for their conductivity and corrosion resistance. Quartz (silicon dioxide): the eye ears and brain need A key component in glass silicon to function properly used in computer displays and other parts of the computer. Bauxite (aluminum oxide) found in Jamaica: Jamaican brains must drink water with bauxite as source of aluminum, used in various motherboard components. Chalcopyrite (copper iron sulfide): as a Personal Computer motherboard the human brainn must be supplied with a source of copper. Cassiterite (tin oxide): the brain as a PC needs a primary source of tin. Sphalerite (zinc sulfide): the brain can't function without a source of zinc and indium. Mica is a group of naturally occurring, layered silicate minerals characterized by their ability to split into thin, flexible sheets, and are known for their use in various applications, including cosmetics, insulation, and electronics Used in coatings and other materials the human brain need mica and cobalt used in batteries. PC Motherboards also contain trace amounts of other elements like antimony, barium, bismuth, boron, cobalt, europium, gallium, germanium, indium, lithium, manganese, nickel, niobium, palladium, platinum, rhodium, ruthenium, selenium, silver, tantalum, terbium, thorium, titanium, vanadium, and yttrium which the human brain need for proper computation. all these minerals can be purchased from iherb.com a vital kosher supplement with 71 minerals called Nature's Plus Trace Minerals i ordered from iherb.com with no regret Natures Plus Trace Minerals supplement facts 1 Aluminum 2 Antimony 3 Barium 4 Beryllium 5 Bismuth 6 Boron 7 Bromine 8 Calcium 9 Cerium 10 Cesium 11 Chlorine 12 Chromium 13 Cobalt 14 Copper 15 Dysprosium 16 Erbium 17 Europium 18 Fluorine 19 Gadolinium 20 Gallium 21 Germanium 22 Gold 23 Hafnium 24 Holmium 25 indium 26 iodine 27 iridium 28 iron 29 Lanthanum 30 Lithium 31 Lutetium 32 Magnesium 33 Manganese 34 Molybdenum 35 Neodymium 36 Nickel 37 Niobium 38 Nitrogen 39 Oxygen 40 Osmium 41 Palladium 42 Phosphorus 43 Platinum 44 Potassium 45 Praseodymium 46 Rhenium 47 Rhodium 48 Rubidium 49 Ruthenium 50 Samarium 51 Scandium 52 Selenium 53 Silicon 54 Silver 56 Sodium 57 Strontium 58 Sulfur 59 Tantalum Tellurium 60 Terbium 61 Thallium 62 Thorium 63 Thulium 64 Tin 65 Titanium 66 Tungsten 67 Vanadium 68 Ytterbium 69 Yttrium 70 Zinc 71 Zirconium Some studies suggest silica may help protect against memory loss and reduce the risk of Alzheimer's disease by potentially counteracting the effects of aluminum promoting the excretion of aluminum in the brain. The reaction of the brain to the presence of the silica was examined by light and electronmicroscopy up to one year after the injection. The presence of silica particles in the brain resulted in the proliferation of fibrous astrocytes and macrophages and strongly stimulated the production of collagen fibers after the age of 40 the brain shrinks at a rate of 5% per decade atrophy to avoid decay drink charcoal smoothies because the brain is mostly made of polyunsaturated fatty acids and polyunsaturatted fatty acids are mostly made of carbon in nomine Patris et FiLii et Spiritus Sancti peace be still
https://www.youtube.com/watch?v=kMKc8nfPATI
The Brain
https://www.youtube.com/watch?v=CurW-sIQPxU&list=LL&index=1
Human Nervous System (Part 2) - Brain (Animation)
https://www.youtube.com/watch?v=P4_bULdls6w&t=4373s
Secrets Of The Human Brain. A Journey Into the Unknown
https://www.youtube.com/watch?v=_aCCsRCw78g
Introduction: Neuroanatomy Video Lab - Brain Dissections
https://www.youtube.com/watch?v=cMim0uU1yzA
What happens to your brain as you age
https://www.youtube.com/watch?v=s5UuNa8AaDQ
"It is in this Part of the Brain where GOD Communicates with Men" Barbara O'Neill
https://www.youtube.com/watch?v=HM1qps2qLlI
Korean researchers find key cause of bipolar disorder
https://www.youtube.com/watch?v=vpXrgJ5aj_4&t=79s
How Does a Child's Brain Develop? | Susan Y. Bookheimer PhD | UCLAMDChat
https://www.youtube.com/watch?v=SvBfAqk70LU
Dr. Octavio Choi presents Brain Basics: An Introduction to Cognitive Neuroscience
https://www.youtube.com/watch?v=SZLAUu8S-g0
BIO 168 Module 11 - The Cerebrum
https://www.youtube.com/watch?v=ZP5RCfegFQ0
An Introduction to the Brain
https://www.youtube.com/watch?v=pe3ndaTKjuM
Neuroplasticity Explained: How to Rewire Your Brain for Mental Strength
https://www.youtube.com/watch?v=yQ6VOOd73MA
Your Brain: Who's in Control? | Full Documentary | NOVA | PBS

The Krebs cycle The citric acid cycle—also known as the Krebs cycle, Szent–Györgyi–Krebs cycle, or TCA cycle (tricarboxylic acid cycle)—is a series of biochemical reactions to release the energy stored in nutrients through the oxidation of acetyl-CoA derived from carbohydrates, fats, proteins, and alcohol. The chemical energy released is available in the form of ATP. The Krebs cycle is used by organisms that respire (as opposed to organisms that ferment) to generate energy, either by anaerobic respiration or aerobic respiration. In addition, the cycle provides precursors of certain amino acids, as well as the reducing agent NADH, that are used in numerous other reactions. Its central importance to many biochemical pathways suggests that it was one of the earliest components of metabolism. Even though it is branded as a "cycle", it is not necessary for metabolites to follow only one specific route; at least three alternative segments of the citric acid cycle have been recognized. The name of this metabolic pathway is derived from the citric acid (a tricarboxylic acid, often called citrate, as the ionized form predominates at biological pH[6]) that is consumed and then regenerated by this sequence of reactions to complete the cycle. The cycle consumes acetate (in the form of acetyl-CoA) and water, reduces NAD+ to NADH, releasing carbon dioxide. The NADH generated by the citric acid cycle is fed into the oxidative phosphorylation (electron transport) pathway. The net result of these two closely linked pathways is the oxidation of nutrients to produce usable chemical energy in the form of ATP. In eukaryotic cells, the citric acid cycle occurs in the matrix of the mitochondrion. In prokaryotic cells, such as bacteria, which lack mitochondria, the citric acid cycle reaction sequence is performed in the cytosol with the proton gradient for ATP production being across the cell's surface (plasma membrane) rather than the inner membrane of the mitochondrion. For each pyruvate molecule (from glycolysis), the overall yield of energy-containing compounds from the citric acid cycle is three NADH, one FADH2, and one GTP.
https://www.youtube.com/watch?v=ubzw64PQPqM
KREBS CYCLE MADE SIMPLE - TCA Cycle Carbohydrate Metabolism Made Easy
https://www.youtube.com/watch?v=JOncWQUpMzc
Krebs Cycle | Made Easy!
https://www.youtube.com/watch?v=juM2ROSLWfw
Krebs / citric acid cycle | Cellular respiration | Biology | Khan Academy
https://www.youtube.com/watch?v=Lf4irlyN1eE
Metabolism Overview

Thalamus (pl.: thalami; from Greek θάλαμος, "chamber") is a large mass of gray matter on the lateral walls of the third ventricle forming the dorsal part of the diencephalon (a division of the forebrain). Nerve fibers project out of the thalamus to the cerebral cortex in all directions, known as the thalamocortical radiations, allowing hub-like exchanges of information. It has several functions, such as the relaying of sensory and motor signals to the cerebral cortex and the regulation of consciousness, sleep, and alertness. Anatomically, it is a paramedian symmetrical structure of two halves (left and right), within the vertebrate brain, situated between the cerebral cortex and the midbrain. It forms during embryonic development as the main product of the diencephalon, as first recognized by the Swiss embryologist and anatomist Wilhelm His Sr. in 1893.
https://www.youtube.com/watch?v=L8SezbBHWJI
Neurology | Thalamus Anatomy & Function

The heart is a muscular organ found in most animals. The human heart beats 60 times a minute, this organ pump blood through the blood vessels of the circulatory system. The pumped blood carries oxygen and nutrients to the body, while carrying metabolic waste such as carbon dioxide to the lungs. In humans, the heart is approximately the size of a closed fist and is located between the lungs, in the middle compartment of the chest, called the mediastinum. In humans, other mammals, and birds, the heart is divided into four chambers: upper left and right atria and lower left and right ventricles. Commonly, the right atrium and ventricle are referred together as the right heart and their left counterparts as the left heart. Fish, in contrast, have two chambers, an atrium and a ventricle, while most reptiles have three chambers. In a healthy heart, blood flows one way through the heart due to heart valves, which prevent backflow. The heart is enclosed in a protective sac, the pericardium, which also contains a small amount of fluid. The wall of the heart is made up of three layers: epicardium, myocardium, and endocardium. In all vertebrates, the heart has an asymmetric orientation, almost always on the left side. According to one theory, this is caused by a developmental axial twist in the early embryo. The heart pumps blood with a rhythm determined by a group of pacemaker cells in the sinoatrial node. These generate an electric current that causes the heart to contract, traveling through the atrioventricular node and along the conduction system of the heart. In humans, deoxygenated blood enters the heart through the right atrium from the superior and inferior venae cavae and passes to the right ventricle. From here, it is pumped into pulmonary circulation to the lungs, where it receives oxygen and gives off carbon dioxide. Oxygenated blood then returns to the left atrium, passes through the left ventricle and is pumped out through the aorta into systemic circulation, traveling through arteries, arterioles, and capillaries—where nutrients and other substances are exchanged between blood vessels and cells, losing oxygen and gaining carbon dioxide—before being returned to the heart through venules and veins. The heart beats at a resting rate close to 72 beats per minute. Exercise temporarily increases the rate, but lowers it in the long term, and is good for heart health. Cardiovascular disease are the most common cause of death globally as of 2008, accounting for 30% of all human deaths. Of these more than three-quarters are a result of coronary artery disease and stroke. Risk factors include: smoking, being overweight, little exercise, high Low Density Lipoprotein bad cholesterol, high blood pressure, and poorly controlled diabetes, among others. Cardiovascular disease do not frequently have symptoms but may cause chest pain or shortness of breath. Diagnosis of heart disease is often done by the taking of a medical history, listening to the heart-sound with a stethoscope, as well as with ECG, and echocardiogram which use ultrasound. Specialists who focus on disease of the heart are called cardiologists, although many specialty of medicine may be involved in treatment. The heart, in contrast, doesn't get exposed to many carcinogens, just those in the blood. That, combined with the fact that heart cells do not often replicate, is why you don't see much cancer of the heart muscle. Indeed, according to cancer statistic, cancer does not appear to occur at any measurable rate. After birth, the heart makes about 1% to 2% new heart cells per year, a process that continues for the first half of life. In the second half of life, however, the heart cells lose their ability to divide. This degree of myocyte formation ensures that the entire cell population of the heart is replaced approximately every 4.5 years. nearly 30% of the heart can be replaced within 1 year if you take you nitrogen oxide , Hydrogen peroxide  and DNA supplements if not you suffer heart attack; scientists found that new heart cells were generated from pre-existing cardiomyocytes rather than progenitor cells. Cardiomyocytes, or cardiac muscle cells, are the specialized cells responsible for the heart's contractile force and its ability to pump blood throughout the body. They are striated, branched, and connected by specialized junctions called intercalated discs, allowing them to contract in a coordinated, involuntary rhythm. The unique structure of cardiomyocytes enable their powerful and synchronous function. Sarcomeres: The fundamental contractile units of muscle cells, sarcomeres give cardiomyocytes their striated, or striped, appearance. They are composed of thick (myosin) and thin (actin) protein filaments that slide past each other to cause muscle contraction. Intercalated discs: These complex junctions connect the ends of adjacent cardiomyocytes and ensure the heart muscle function as a cohesive unit, or syncytium. Gap junctions: These channels allow for the rapid passage of ions and electrical impulses between cells, enabling synchronized contraction. Desmosomes: These spot-weld junctions strongly anchor cells together, preventing them from pulling apart during contraction. T-tubules: These microscopic tunnels of the cell membrane transmit electrical impulses deep into the cell to trigger the release of calcium. Mitochondria: Heart muscle cells are packed with large, elongated mitochondria, which produce the vast amount of energy (ATP) needed for continuous contraction. Function Cardiomyocyte function is regulated by a finely tuned process of electrical and chemical signals. Excitation-contraction coupling: An action potential (electrical impulse) triggers voltage-gated calcium channels on the cell membrane to open. This causes a smaller influx of extracellular calcium, which in turn triggers a much larger release of calcium from the cell's internal stores in the sarcoplasmic reticulum. Contraction and relaxation: The increase in intracellular calcium allows myosin and actin filaments to interact, causing the sarcomeres to shorten and the cell to contract. The relaxation phase is driven by pumps that remove calcium from the cell. Automaticity: Specialized cardiomyocytes in the sinoatrial (SA) node function as the heart's natural pacemaker, spontaneously generating electrical impulse that set the heart's rhythm. Specialized subtypes Different regions of the heart have distinct cardiomyocyte subtypes that contribute to overall function.  Atrial and ventricular cardiomyocytes: These "working" cells form the bulk of the heart muscle and have different sizes and electrophysiological property. Ventricular myocytes are larger and generate the forceful contractions needed to pump blood to the body and lungs. The ventricular cardiac myocyte is a specialized cell type found in the cardiac tissue. Specifically, these cells are located in the ventricles of the heart, which are the bottom chambers responsible for pumping blood out of the heart to the lungs and the rest of the body. Conducting system cells: These specialized cells, which include pacemaker and Purkinje cells, are optimized for generating and rapidly transmitting electrical signals throughout the heart. Cardiomyocyte health is central to cardiac function, and their limited ability to regenerate in adults means that injury can lead to serious conditions. Cardiomyopathy: These are disease of the heart muscle that impair its ability to pump blood effectively. Examples include dilated, hypertrophic, and arrhythmogenic cardiomyopathy. Myocardial infarction (heart attack): When blood flow to the heart muscle is blocked, it can cause the death of cardiomyocytes, leading to tissue damage. Heart failure: The inability of the heart to pump enough blood to meet the body's needs often result from the progressive loss or dysfunction of cardiomyocytes. Cardiomyocytes are the specialized muscle cells that make up the heart, responsible for its rhythmic contraction and pumping blood throughout the body. These cells are striated and branched, connected by specialized intercalated discs containing gap junctions for electrical communication and desmosomes for structural integrity, allowing the heart to function as a single, coordinated unit. Cardiomyocytes contain contractile proteins that slide past each other to generate force and are rich in mitochondria to meet their high energy demand. Key Characteristic: Contractile: Cardiomyocytes generate the mechanical force needed to pump blood. Striated: They have a banded appearance due to the arrangement of contractile proteins, similar to skeletal muscle. Branched: Cardiomyocytes branched structure, along with intercalated discs, allows for synchronized contractions. Involuntary: Their contraction is controlled by the body's nervous system, not conscious thought. Rich in Mitochondria: They require a constant and abundant supply of energy, provided by numerous mitochondria. Electrical Coupling: Gap junctions within intercalated discs allow electrical impulses (action potentials) to spread quickly from cell to cell, coordinating the heart's beat. Desmosomes: These anchor cells together, providing the structural strength necessary for the heart to withstand the forces of contraction. Function in the Heart: Pumping Blood: The primary role of cardiomyocytes is to contract and relax in a coordinated cycle to effectively pump blood and oxygenated nutrients to body tissue. Electrical Control: Specialized cardiomyocytes form the cardiac conduction system, which control the heart's rhythmic beating. Importance and Pathologies: Heart Failure: A significant loss of cardiomyocytes due to injury or disease can lead to heart failure, as the heart is unable to pump enough blood to meet the body's need. Hypertrophy: In response to increased demand, cardiomyocytes can undergo hypertrophy (enlargement), but excessive hypertrophy can contribute to heart failure. Scientists estimated a yearly renewal rate of less than 1% during normal, healthy heart condition. The rate of cell regeneration, they found, declined with age. The most abundant loss of cardiomyocytes occur during a myocardial infarction, when the blood supply to the heart is obstructed, and the affected myocardium succumb to cell death. The myocardial connective tissue maintaining the functional integrity of the heart mainly consist of collagen type I 80% & collagen type III 20%. Along with proteoglycans, elastin and glycoproteins, – with heterotypic structures of types I and III collagen (but including small amounts of types V and VI) – arranged in discontinuous fibers of variable diameters in interlacing fiber bundles or defined lamellar patterns. Heart stem cells, or cardiac stem cells, can come from various sources, including bone marrow, peripheral blood, and even the heart itself, with research exploring their potential for cardiac repair and regeneration. Bone Marrow Mononuclear Cells (BMMNCs): A mixture of cells from bone marrow, including mesenchymal stem cells, are being explored for heart disease treatment. Bone Marrow-Derived Cells: Studies suggest that a subpopulation of bone marrow-derived cells can differentiate into cardiac myocytes (heart muscle cells). Cardiac Stem Cells (CSCs): These are stem cells found within the heart tissue itself, and research is ongoing to understand their role in cardiac regeneration. Cardiospheres: When cardiac stem cells derived from biopsies are allowed to grow in vitro, they form spheres, which are thought to be more committed to a cardiac stem cell fate. Epicardium: The outermost surface of the heart, which play a role in coronary vasculature formation and retain regenerative potential 3. Other Sources: Peripheral Blood: Stem cells can be found in the bloodstream, which can be a source for stem cell therapy. Umbilical Cord Blood: Mayo Clinic report that umbilical cord blood can be a source of stem cells. Embryonic Stem Cells (ESCs): These are stem cells derived from embryos, which can differentiate into various cell type, including heart cells. Silica assures the elasticity of the aorta making the aorta resilient in case of high blood pressure i supplement with gravel gastroliths & own a rock crusher , amongst other minerals gravel contain 75% silica which prevent heart failure, The cells in your heart muscle have an extremely low replacement rate, with many lasting a lifetime.
https://www.youtube.com/watch?v=3_PYnWVoUzM
What happens during a heart attack? - Krishna Sudhir
https://www.youtube.com/watch?v=pd3TFB0wOI0&t=31s
The heart makers
https://www.youtube.com/watch?v=Mv3dKgwbJ7U
Anatomy and Physiology of The Heart
https://www.youtube.com/watch?v=2YgRJ70ZIyU
New Research Into Heart Health | Breakthrough
https://www.youtube.com/watch?v=dgAbpwp9gF8
Cardiovascular | Structures and Layers of the Heart
https://www.youtube.com/watch?v=SC5fKdrYi6w
Histology of the Heart – Histology | Lecturio
https://www.youtube.com/watch?v=KPKLq-LQjbc
The Difference Between Cardiac Arrest, Heart Attack, and Heart Failure - 3D Animation
https://www.youtube.com/watch?v=1kX6Tp8CWFw
Cardiovascular | Electrophysiology | Intrinsic Cardiac Conduction System
https://www.youtube.com/watch?v=_SDXsjM23_E
Heart transplantation
https://www.youtube.com/watch?v=eDmlWAaDxVg
Open Heart Surgery | Inside the OR

The human Body God created the human body when God created Adam in the garden of Eden, in this video we take a look at the Kidneys which produce red blood cells and filter out waste fluids. The human body can withstand a wide range of external temperatures, but there's a limit to how high core body temperature can rise before it becomes fatal. While the normal body temperature is around 98.6°F (37°C), the body's ability to regulate temperature is challenged at higher temperatures, especially when combined with humidity. Generally, a core body temperature of 107.6°F (42°C) can lead to serious health consequences, including brain damage and cardio-respiratory collapse, and 109.4°F (43°C) is considered the upper limit for survival, with a near-certain death rate // a living Human has access to the 2 dimensions the spirit realm and the earth realm 2 dimensions accessible in 1 human body as long as the human being is alive when you die and the soul leaves the body the spirit body has accessibility to multiple spirit dimensions in the spirit realm , once dead the soul does not have access to the earth realm it is written in the Holy King James Bible epistle to the Ephesians of saint Paul the apostle 50 AD Anno Domini in the year of our Lord Jesus Christ 1 Corinthians 15:35-40 But some man will say, How are the dead raised up? and with what body do they come? 36 Thou fool, that which thou sowest is not quickened, except it die: 37 And that which thou sowest, thou sowest not that body that shall be, but bare grain, it may chance of wheat, or of some other grain: 38 But God giveth it a body as it hath pleased him, and to every seed his own body. 39 All flesh is not the same flesh: but there is one kind of flesh of men, another flesh of beasts, another of fishes, and another of birds. 40 There are also celestial bodies, and bodies terrestrial: but the glory of the celestial is one, and the glory of the terrestrial is another. amen
https://www.youtube.com/watch?v=DXK2wuQAbxg
Human Organs in the Body | 24 Hours to Master HUMAN ANATOMY
https://www.youtube.com/watch?v=CShAIAD-ask
How Your Kidneys Work
https://www.youtube.com/watch?v=SZ3BZBBC-Qc
How is urine produced in the body?KIDNEY, NEPHRON, BLADDER FUNCTION|Anatomy of the Urinary System
https://www.youtube.com/watch?v=Fo6MxtlVgy4
Do You Know These Incredible Facts About the Human Body?
https://www.youtube.com/watch?v=QMP6soeKrPQ&list=LL&index=7&t=9874s
🔴 Inside Us Live: Human Anatomy & Organ Systems

Thyroid God alighty created the Thyroid of Adam and Eve each distinct with male & female hormones thyroid problems significantly impact blood pressure. An overactive thyroid (hyperthyroidism) can cause high blood pressure by increasing heart rate and cardiac output, while an underactive thyroid (hypothyroidism) can also lead to hypertension due to a weakened heart muscle, increased blood vessel stiffness, and reduced heart function. Treating the underlying thyroid disorder is crucial, as it can often reverse the associated blood pressure changes, thyroid gland, is an endocrine gland in vertebrates. In humans, it is a butterfly-shaped gland located in the neck below the Adam's apple. It consists of two connected lobes. The lower two thirds of the lobes are connected by a thin band of tissue called the isthmus (pl.: isthmi). Microscopically, the functional unit of the thyroid gland is the spherical thyroid follicle, lined with follicular cells (thyrocytes), and occasional parafollicular cells that surround a lumen containing colloid. The thyroid gland secretes three hormones: the two thyroid hormones – triiodothyronine (T3) and thyroxine (T4) – and a peptide hormone, calcitonin. The thyroid hormones influence the metabolic rate and protein synthesis and growth and development in children. Calcitonin plays a role in calcium homeostasis. Secretion of the two thyroid hormones is regulated by thyroid-stimulating hormone (TSH), which is secreted from the anterior pituitary gland. TSH is regulated by thyrotropin-releasing hormone (TRH), which is produced by the hypothalamus. Thyroid disorders include hyperthyroidism, hypothyroidism, thyroid inflammation (thyroiditis), thyroid enlargement (goitre), thyroid nodules, and thyroid cancer. Hyperthyroidism is characterized by excessive secretion of thyroid hormones: the most common cause is the autoimmune disorder Graves' disease. Hypothyroidism is characterized by a deficient secretion of thyroid hormones: the most common cause is iodine deficiency. In iodine-deficient regions, hypothyroidism (due to iodine deficiency) is the leading cause of preventable intellectual disability in children. In iodine-sufficient regions, the most common cause of hypothyroidism is the autoimmune disorder Hashimoto's thyroiditis if you loose your voice its due to no minerals in the trachea i started ingesting gastroliths have since noticed an improvement in my voice i now sing at a higher pitch ever thank God Almighty for the gastroliths cement & gravel i would have no organ voice if it were not for the gastroliths it is written in the Holy King James Bible epistle to the Ephesians of saint Paul the apostle 50 AD Anno Domini in the year of our Lord Jesus Christ 1 Corinthians 15:35-40 But some man will say, How are the dead raised up? and with what body do they come? 36 Thou fool, that which thou sowest is not quickened, except it die: 37 And that which thou sowest, thou sowest not that body that shall be, but bare grain, it may chance of wheat, or of some other grain: 38 But God giveth it a body as it hath pleased him, and to every seed his own body. 39 All flesh is not the same flesh: but there is one kind of flesh of men, another flesh of beasts, another of fish, and another of birds. 40 There are also celestial bodies, and bodies terrestrial: but the glory of the celestial is one, and the glory of the terrestrial is another. amen

Trachea The trachea (pl.: tracheae or tracheas), also known as the windpipe, is a cartilaginous tube that connect the larynx to the bronchi of the lungs, allowing the passage of air, and so is present in almost all animals' lungs. The trachea extends from the larynx and branches into the two primary bronchi. At the top of the trachea, the cricoid cartilage attaches it to the larynx. The trachea is formed by a number of horseshoe-shaped rings, joined together vertically by overlying ligaments, and by the trachealis muscle at their ends. The epiglottis closes the opening to the larynx during swallowing. The trachea begins to form in the second month of embryo development, becoming longer and more fixed in its position over time. Its epithelium is lined with column-shaped cells that have hair-like extensions called cilia, with scattered goblet cells that produce protective mucins. The trachea can be affected by inflammation or infection, usually as a result of a viral illness affecting other parts of the respiratory tract, such as the larynx and bronchi, called croup, that can result in a cough. Infection with bacteria usually affects the trachea only and can cause narrowing or even obstruction. As a major part of the respiratory tract, the trachea, when obstructed, prevents air from entering the lungs; thus, a tracheostomy may be required. Additionally, during surgery, if mechanical ventilation is required during anaesthesia, a tube is inserted into the trachea: this is called tracheal intubation. The word trachea is used to define a very different organ in invertebrates than in vertebrates. Insects have an open respiratory system made up of spiracles, tracheae, and tracheoles to transport metabolic gases to and from tissue if you loose your voice its due to no minerals in the trachea i started ingesting gastroliths have since noticed an improvement in my voice i now sing at a higher pitch ever thank God Almighty for the gastroliths cement & gravel i would have no organ voice if it were not for the gastroliths it is written in the Holy King James Bible epistle to the Ephesians of saint Paul the apostle 50 AD Anno Domini in the year of our Lord Jesus Christ 1 Corinthians 15:35-40 But some man will say, How are the dead raised up? and with what body do they come? 36 Thou fool, that which thou sowest is not quickened, except it die: 37 And that which thou sowest, thou sowest not that body that shall be, but bare grain, it may chance of wheat, or of some other grain: 38 But God giveth it a body as it hath pleased him, and to every seed his own body. 39 All flesh is not the same flesh: but there is one kind of flesh of men, another flesh of beasts, another of fish, and another of birds. 40 There are also celestial bodies, and bodies terrestrial: but the glory of the celestial is one, and the glory of the terrestrial is another. amen