felykotagbia.com - TEETH REGROW

Teeth regrow new medicine quite literally regrows teeth & was developed by a team of Japanese researchers, as reported by New Atlas. The research has been led by Katsu Takahashi, head of dentistry and oral surgery at Kitano Hospital. The intravenous drug deactivates the uterine sensitization-associated gene-1 (USAG-1) protein that suppresses tooth growth. Blocking USAG-1 from interacting with other proteins triggers bone growth and, voila, you got yourself some brand-new chompers. Pretty cool, right? Human trials start in September, but the drug has been highly successful when treating ferrets and mice and did its job with no serious side effects. Of course, the usual caveat applies. Humans are not mice or ferrets, though researchers seem confident that it’ll work on homo sapiens. This is due to a 97 percent similarity in how the USAG-1 protein works when comparing humans to other species. September’s clinical trial will include adults who are missing at least one molar but there’s a secondary trial coming aimed at children aged two to seven. The kids in the second trial will all be missing at least four teeth due to congenital tooth deficiency. Finally, a third trial will focus on older adults who are missing “one to five permanent teeth due to environmental factors.” Takahashi and his fellow researchers are so optimistic about this drug that they predict the medicine will be available for everyday consumers by 2030. While this is the first drug that can fully regrow missing teeth, the science behind it builds on top of years of related research. Takahashi, after all, has been working on this since 2005. Recent advancements in the field include regenerative tooth fillings to repair diseased teeth and stem cell technology to regrow the dental tissue of children .

The prevalence and severity of periodontal disease increase significantly with age, largely due to the cumulative exposure to bacterial plaque, long-term immune-inflammatory responses, and structural changes in gum tissue over time. Seniors (65+) approx 70% - 75% Highest rates of severe disease ; significant bone resorption, tooth mobility, and history of tooth loss. Why Periodontal Risk Escalates with Age Cumulative Exposure: Periodontitis is a slow, progressive condition. Decades of bacterial biofilm accumulation create an ongoing inflammatory cycle that gradually degrade periodontal ligament & surrounding bone. Immunosenescence: Aging alter the immune system's balance. Older adults often experience low-grade, chronic systemic inflammation ("inflammaging"), which lead to an exaggerated inflammatory response to oral bacteria, accelerating tissue & bone loss. Salivary Flow Reduction: Saliva contain crucial antimicrobial protein & bicarbonate buffers that neutralize oral acids to slow bacterial growth. Age-related change high sugar intake no gravel gastrolith intake —and especially medication commonly prescribed in later life—frequently reduce salivary output (xerostomia/dry mouth). Systemic Health Co-Factors: Chronic metabolic condition that become more common with age, such as Type 2 diabetes, directly impair microvascular circulation in gum tissue, weakening the body's local repair mechanism May the Holy Roman Catholic Church refrain from slave trading sugar so be blessed by God the Father God the Son & God the Holy Spirit ⁺‧₊⋆♱⋆₊‧⁺Hallelujah Hallelujah Blessed be the word of the Lord for Christ is risen Hallelujah Hallelujah peace be still in Nomine Patris et FiLii et Spiritus Sancti amen & amen
https://www.youtube.com/watch?v=h_uThS-V9tA
Drug to regrow teeth may be on market by 2030 | NewsNation Live
https://www.youtube.com/watch?v=_-q6pQ52FFs
The End of Dentures? How iPS Cells Could Grow Back Bones & Teeth w/ Dr. Hiroshi Egusa
https://www.youtube.com/watch?v=uxxw0zYvkXs&t=77s
Can We Regenerate Our Teeth?
https://www.youtube.com/watch?v=QZi8od-WMWE
Regrowing Teeth In Old Age Is Possible! Human Trial Starts This Year
https://www.youtube.com/watch?v=3lhfms_7OKg
This drug could allow you to grow new teeth | Latest News | WION
https://www.youtube.com/watch?v=h_uThS-V9tA
Drug to regrow teeth may be on market by 2030 | NewsNation Live
https://www.youtube.com/watch?v=atIfRGiITI0
How AI in dentistry is transforming smiles
https://www.youtube.com/watch?v=GZ-DFAzzrBA
Dental Breakthroughs To Save Your Smile - Medical Frontiers
https://www.youtube.com/watch?v=McOVhnsdlYM
How Effective Is Your Toothpaste? | Talking Point | Full Episode

The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a physical and a functional standpoint. It started in 1990 and was completed in 2003. It was the world's largest collaborative biological project. Planning for the project began in 1984 by the US government, and it officially launched in 1990. It was declared complete on 14 April 2003, and included about 92% of the genome. Level "complete genome" was achieved in May 2021, with only 0.3% of the bases covered by potential issues. The final gapless assembly was finished in January 2022. Funding came from the US government through the National Institutes of Health (NIH) as well as numerous other groups from around the world. A parallel project was conducted outside the government by the Celera Corporation, or Celera Genomics, which was formally launched in 1998. Most of the government-sponsored sequencing was performed in twenty universities and research centres in the United States, the United Kingdom, Japan, France, Germany, and China, working in the International Human Genome Sequencing Consortium (IHGSC). The Human Genome Project originally aimed to map the complete set of nucleotides contained in a human haploid reference genome, of which there are more than three billion. The genome of any given individual is unique; mapping the human genome involved sequencing samples collected from a small number of individuals and then assembling the sequenced fragments to get a complete sequence for each of the 23 human chromosome pairs (22 pairs of autosomes and a pair of sex chromosomes, known as allosomes). Therefore, the finished human genome is a mosaic, not representing any one individual. Much of the project's utility comes from the fact that the vast majority of the human genome is the same in all humans. The Human Genome Project ultimately cost approximately $2.7 billion, although it was initially budgeted at $3 billion. This international effort, which mapped the entire human genome, took 13 years to complete and significantly transformed genomic sequencing technology, enabling much cheaper and faster sequencing in the decades that followed. Key detail about the project's cost:Total cost: Around $2.7 billion. Duration: The project lasted for 13 years. Purpose: The goal was to sequence the human genome. Technological impact: The massive investment in the Human Genome Project spurred the development of new sequencing technologies, which drastically reduced the cost and time of sequencing a human genome. Cost reduction since: Today, the cost of sequencing a human genome is a fraction of what it was at the time of the Human Genome Project and continues to decrease blessed be the numerous scientist who developed the Human Genome Project in nomine Patris et FiLii et Spiritus Sancti missa orationis peace be still amen
Developed on Lenovo M800 Windows 10 Shot with Samsung Galaxy Ao4S edited with Davinci Resolve & Photoshop cs 26.10.0