Chirality In chemistry, a molecule or ion is called chiral if it cannot be superposed on its mirror image by any combination of rotations, translations, and some conformational changes. This geometric property is called chirality . The terms are derived from Ancient Greek χείρ (cheir) 'hand'; which is the canonical example of an object with this property. A chiral molecule or ion exists in two stereoisomers that are mirror images of each other,[5] called enantiomers; they are often distinguished as either "right-handed" or "left-handed" by their absolute configuration or some other criterion. The two enantiomers have the same chemical properties, except when reacting with other chiral compounds. They also have the same physical properties, except that they often have opposite optical activities. A homogeneous mixture of the two enantiomers in equal parts is said to be racemic, and it usually differs chemically and physically from the pure enantiomers. Chiral molecules will usually have a stereogenic element from which chirality arises. The most common type of stereogenic element is a stereogenic center, or stereocenter. In the case of organic compounds, stereocenters most frequently take the form of a carbon atom with four distinct (different) groups attached to it in a tetrahedral geometry. Less commonly, other atoms like N, P, S, and Si can also serve as stereocenters, provided they have four distinct substituents (including lone pair electrons) attached to them. A given stereocenter has two possible configurations (R and S), which give rise to stereoisomers (diastereomers and enantiomers) in molecules with one or more stereocenter. For a chiral molecule with one or more stereocenter, the enantiomer corresponds to the stereoisomer in which every stereocenter has the opposite configuration. An organic compound with only one stereogenic carbon is always chiral. On the other hand, an organic compound with multiple stereogenic carbons is typically, but not always, chiral. In particular, if the stereocenters are configured in such a way that the molecule can take a conformation having a plane of symmetry or an inversion point, then the molecule is achiral and is known as a meso compound. Molecules with chirality arising from one or more stereocenters are classified as possessing central chirality. There are two other types of stereogenic elements that can give rise to chirality, a stereogenic axis (axial chirality) and a stereogenic plane (planar chirality). Finally, the inherent curvature of a molecule can also give rise to chirality (inherent chirality). These types of chirality are far less common than central chirality. BINOL is a typical example of an axially chiral molecule, while trans-cyclooctene is a commonly cited example of a planar chiral molecule. Finally, helicene possesses helical chirality, which is one type of inherent chirality. Chirality is an important concept for stereochemistry and biochemistry. Most substances relevant to biology are chiral, such as carbohydrates (sugars, starch, and cellulose), all but one of the amino acids that are the building blocks of proteins, and the nucleic acids. Naturally occurring triglycerides are often chiral, but not always. In living organisms, one typically finds only one of the two enantiomers of a chiral compound. For that reason, organisms that consume a chiral compound usually can metabolize only one of its enantiomers. For the same reason, the two enantiomers of a chiral pharmaceutical usually have vastly different potencies or effects.
https://www.youtube.com/watch?v=_wDIe0XEmwI
Mirror Molecules: The Symmetry Rule Life Never Breaks
Dolly the sheep the first cloned mamal now there are cat and dog clones all around the world Dolly (5 July 1996 – 14 February 2003) was a female Finn-Dorset sheep and the first mammal that was cloned from an adult somatic cell. She was cloned by associates of the Roslin Institute in Scotland, using the process of nuclear transfer from a cell taken from a mammary gland. Her cloning proved that a cloned organism could be produced from a mature cell from a specific body part. Contrary to popular belief, she was not the first animal to be cloned. The employment of adult somatic cells in lieu of embryonic stem cells for cloning emerged from the foundational work of John Gurdon, who cloned African clawed frogs in 1958 with this approach. The successful cloning of Dolly led to widespread advancements within stem cell research, including the discovery of induced pluripotent stem cells. Dolly lived at the Roslin Institute throughout her life and produced several lambs. She was euthanized at the age of six years due to a progressive lung disease. No cause which linked the disease to her cloning was found. Dolly's body was preserved and donated by the Roslin Institute in Scotland to the National Museum of Scotland, where it has been regularly exhibited since 2003.
https://www.youtube.com/watch?v=jDi-eF0_f8s
Incredible science behind cloning Dolly the sheep | 60 Minutes Australia
https://www.youtube.com/watch?v=tELZEPcgKkE
The Story of Dolly the Cloned Sheep | Retro Report | The New York Times
https://www.youtube.com/watch?v=c3QWTFpuyqg&t=679s
South Korea’s Dog Cloning Industry
https://www.youtube.com/watch?v=dfqwUlnsGvY
Clone- National Geographic
https://www.youtube.com/watch?v=_LFupw-TYaA
The History Of Cloning Explained
https://www.youtube.com/watch?v=hL9vhlcPNsc
How a Sheep Named Dolly Sparked a Scientific Revolution | Retro Report
https://www.youtube.com/watch?v=eKdoBH65AMk
Is Cloning Good? The Science & Ethics Of De-Extinction Technology | The Resurrection Quest - Ep 4/4
https://www.youtube.com/watch?v=MkYpmoQdsV0
Playing God: The faces behind controversial baby cloning | 60 Minutes Australia
https://www.youtube.com/watch?v=prTsBspXotg
Chapter 1: Introduction to Microbiology
crispr baby gene editing has led to twin babies Lulu & Nana who cannot get aids i wonder how all the people around the world with aids feel This article is about the prokaryotic antiviral system. For the use in editing genes, see CRISPR gene editing. CRISPR (an acronym for clustered regularly interspaced short palindromic repeats) is a family of DNA sequences found in the genomes of prokaryotic organisms such as bacteria and archaea. These sequences are derived from DNA fragments of bacteriophages that had previously infected the prokaryote. They are used to detect and destroy DNA from similar bacteriophages during subsequent infections. Hence these sequences play a key role in the antiviral (i.e. anti-phage) defense system of prokaryotes and provide a form of acquired immunity. CRISPR is found in approximately 50% of sequenced bacterial genomes and nearly 90% of sequenced archaea. Diagram of the CRISPR prokaryotic antiviral defense mechanism Cas9 (or "CRISPR-associated protein 9") is an enzyme that uses CRISPR sequences as a guide to recognize and open up specific strands of DNA that are complementary to the CRISPR sequence. Cas9 enzymes together with CRISPR sequences form the basis of a technology known as CRISPR-Cas9 that can be used to edit genes within the organisms. This editing process has a wide variety of applications including basic biological research, development of biotechnological products, and treatment of diseases. The development of the CRISPR-Cas9 genome editing technique was recognized by the Nobel Prize in Chemistry in 2020 awarded to Emmanuelle Charpentier and Jennifer Doudna. Heavenly father i pray that God bless all the scientist working on cripr cas 9 may their work help humanity cure aids sickle cells & cancer
https://www.youtube.com/watch?v=b0HvLaXOhEY
Scientist claims he helped create world's first genetically-modified babies
https://www.youtube.com/watch?v=z5XCI27Kx9c
The Ethical Dilemma Of Genome Editing | The CRISPR Revolution
https://www.youtube.com/watch?v=JdMJdTbhLpQ
The Future of Medicine: CRISPR, Drug Prices & Gene Therapy
https://www.youtube.com/watch?v=E8vi_PdGrKg
The Realities of Gene Editing with CRISPR I NOVA I PBS
https://www.youtube.com/watch?v=xzW2rPhIhUk
The CRISPR Revolution: Hacking the Genetic Code
https://www.youtube.com/watch?v=YYrP_wSf7G8
The Sci-Fi World of CRISPR Gene Editing
https://www.youtube.com/watch?v=EH4DmsNiZ3U
Hack your DNA with CRISPR - VPRO documentary - 2018
https://www.youtube.com/watch?v=HG8eSJ5QEnk
Genetically Engineering Your DNA to Cure Disease | Retro Report
https://www.youtube.com/watch?v=8BqRGamGlfE
Curing Diseases or Playing God?
https://www.youtube.com/watch?v=0jILo9y71s0
Scientist who claims to have made gene-edited babies speaks in Hong Kong
https://www.youtube.com/watch?v=ch03XDK7DSE
Jiankui He - The Man Who Used Gene Editing On Babies
https://www.youtube.com/watch?v=EPTeaXMVcyY
Gene Editing Inside the Body Using CRISPR
https://www.youtube.com/watch?v=0OXaanDHENI
You’re Not Ready for What CRISPR Can Do Next
https://www.youtube.com/watch?v=WV91sxtS03k
Inside a CRISPR Lab