Leukemia is a group of blood cancer that usually begin in the bone marrow & produce high number of abnormal blood cells. These blood cells are not fully developed and are called blasts or leukemia cells. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy. TET2 mutations are an unfavorable prognostic factor in Acute myeloid leukemia (rapid growth of abnormal cells in the bone marrow and interfere with blood cell production ) patients with intermediate-risk cytogenetics. TET2 mutations are associated with older age, higher white blood cell & blast counts & lower platelet numbers. TET2 mutations are often lost at relapse, but can rarely be acquired. TET2 mutations are common in Chronic myelomonocytic leukemia, occurring in about 45% of cases. Most cases of TET2-mutated Chronic myelomonocytic leukemia have more than one mutant variant. TET2 mutations occur in about 19% of patients with myelodysplastic (undeveloped blood cells) syndromes. TET2 mutations occur in about 12% of patients with myeloproliferative disorders. TET2 mutations occur in about 24% of patients with secondary AML. Secondary acute myeloid leukemia (sAML) is a type of leukemia that develops after a person has had certain blood conditions or cancer treatments TET2 mutations can lead to abnormal epigenetic patterns, which can affect the differentiation and function of hematopoietic stem cells (HPSCs). This can promote the occurrence of leukemia by affecting cell proliferation TET2 deficiency can also lead to an inflamed immune phenotype, which is associated with several inflammation-based diseases, including cardiovascular disease. Leukemia is caused by overfeeding the body with what the bone don't need like fatty foods to prevent leukemia take supplements as Hydrogen Peroxide Vitamin C & Nitric Oxide
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What is blood cancer?
Liver disease Liver disease, or hepatic disease, is any of many diseases of the liver. If long-lasting it is termed chronic liver disease. Although the diseases differ in detail, liver diseases often have features in common.
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12 Signs of LIVER DISEASE You Can See: Doctor Explains