Sulforaphane

saccharomyces boulardii let medicine be thy food.” Hippocrates 460BC Let supplements be thy medicine & let medicine be thy supplement it is written in the Holy King James Bible the word of the Lord according to saint Moses the prophet of israel 1450 BC Before Christ Genesis 1:29 & God said, Behold, I have given you every herb bearing seed, which is upon the face of all the earth, & every tree, in the which is the fruit of a tree yielding seed; to you it shall be for meat. amen Tantum ergo sacramentum veneremur cernui : et antiquum documentum novo cedat ritui ; praestet fides supplementum sensuum defectui , genitori, genitoque laus et jubilatio , honor , virtus quoque sit et benedictio , procedenti ab utroque , compar sit laudatio. God has provided supplements for healing every human is special to God with each person bearing a signature  peculiar fingerprint ,Saccharomyces boulardii is a tropical yeast first isolated from lychee and mangosteen fruit peel in 1923 by French scientist Henri Boulard. Although early reports claimed distinct taxonomic, metabolic, and genetic properties, S. boulardii is genetically a grouping of S. cerevisiae strains, sharing >99% genomic relatedness, giving the synonym S. cerevisiae var. boulardii S. boulardii is sometimes used as a probiotic with the purpose of introducing beneficial microbes into the large and small intestines and conferring protection against pathogens. It grows at 37 °C (98.6 °F). In addition, the popular genome-editing tool CRISPR-Cas9 was proven to be effective in S. boulardii. Boulard first isolated this yeast after he observed natives of Southeast Asia chewing on the skin of lychee and mangosteen in an attempt to control the symptoms of cholera. In healthy people, S. boulardii has been shown to be nonpathogenic and nonsystemic (it remains in the gastrointestinal tract rather than spreading elsewhere in the body).People commonly use S. boulardii for treating and preventing diarrhea, including rotaviral diarrhea in children. It's also used for other types of diarrhea, acne, a digestive tract infection that can lead to ulcers, and many other conditions, there is good scientific evidence to support many of its other uses.Several clinical trials and experimental studies strongly suggest a place for Saccharomyces boulardii as a biotherapeutic agent for the prevention and treatment of several gastrointestinal diseases. S. boulardii mediates responses resembling the protective effects of the normal healthy gut flora. The multiple mechanisms of action of S. boulardii and its properties may explain its efficacy and beneficial effects in acute and chronic gastrointestinal diseases that have been confirmed by clinical trials.There is increasing evidence that the gastrointestinal microflora is a major regulator of the immune system, not only in the gut, but also in other organs. The nonpathogenic yeast Saccharomyces boulardii has been prescribed in the past 30 years for prophylaxis and treatment of diarrheal diseases caused by bacteria. Importantly, S. boulardii has demonstrated clinical and experimental effectiveness in gastrointestinal diseases with a predominant inflammatory component, indicating that this probiotic might interfere with cellular signaling pathways common in many inflammatory conditions. An increasing number of potential health benefits are being attributed to probiotic treatments S. boulardii is a live yeast used extensively as a probiotic and often marketed as a dietary supplement . Several mechanisms of action have been identified directed against the host as well as pathogenic microorganisms and include regulation of intestinal microbial homeostasis, interference with the ability of pathogens to colonize and infect the mucosa, modulation of local and systemic immune responses, stabilization of the gastrointestinal barrier function and induction of enzymatic activity favoring absorption and nutrition it is written in the Holy King James Bible the revelation of saint John the apostle 50 AD Anno Domini in the year of our Lord Jesus Christ Revelation 22:2 In the midst of the street of it, & on either side of the river, was there the tree of life, which bare twelve manner of fruits, & yielded her fruit every month: & the leaves of the tree were for the healing of the nations. amen
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Mode of action of Saccharomyces boulardii CNCM I-745

Samarium the health benefit of samarium is specifically tied to the radioactive isotope samarium-153 (Sm-153), which is used as a radiopharmaceutical to relieve pain from cancer that has spread to the bones. It is not a dietary supplement or nutrient, and normal samarium is considered toxic in certain forms if ingested or inhaled. How samarium-153 is used for bone pain Radiopharmaceutical: The radioactive isotope Sm-153 is chelated with a compound called lexidronam (EDTMP) and injected intravenously. Targeted therapy: The compound is designed to target and accumulate in areas of new bone growth, which are associated with osteoblastic bone metastases from cancer. Pain relief: Once in the bone, the radioactive samarium-153 emits radiation that helps to relieve pain caused by the cancer. The effects can last for several weeks to months. Suitable patients: This treatment is often used for patients with multiple bone metastases, offering an alternative to external beam radiation for those with widespread disease. Risks and precautions Toxic in other forms: Metallic samarium dust and its compounds can be harmful if inhaled or ingested. The oxide form can cause a variety of symptoms if inhaled or ingested. Myelosuppression: A common side effect of samarium-153 therapy is temporary suppression of bone marrow, which can lower platelet and white blood cell counts. This is monitored by doctors. Radiation safety: Patients receiving the radiopharmaceutical must take precautions to prevent the spread of radioactive material, especially through urine, in the hours following treatment. Use with caution: Healthcare professionals should use caution with samarium-153 in patients with pre-existing conditions, including kidney disease, congestive heart failure, and blood or bone marrow problems it is written in the Holy King James Bible the word of the Lord according to saint Moses the prophet of israel 1450 BC Before Christ Genesis 1:29 & God said, Behold, I have given you every herb bearing seed, which is upon the face of all the earth, & every tree, in the which is the fruit of a tree yielding seed; to you it shall be for meat. amen it is written in the Holy King James Bible the revelation of saint John the apostle 50 AD Anno Domini in the year of our Lord Jesus Christ Revelation 22:2 In the midst of the street of it, & on either side of the river, was there the tree of life, which bare twelve manner of fruits, & yielded her fruit every month: & the leaves of the tree were for the healing of the nations. amen “Let food be thy medicine, and let medicine be thy food.” Hippocrates 460BC Let supplements be thy medicine & let medicine be thy supplement

Selenium Se is an essential micronutrient for animals, though it is toxic in large doses it is written in the Holy King James Bible the word of the Lord according to saint Moses the prophet of israel 1450 BC Before Christ Genesis 1:29 & God said, Behold, I have given you every herb bearing seed, which is upon the face of all the earth, & every tree, in the which is the fruit of a tree yielding seed; to you it shall be for meat. amen In plants, Selenium sometimes occurs in toxic amounts as forage, e.g. locoweed. Selenium is a component of the amino acids selenocysteine & selenomethionine. In humans, selenium is a trace element nutrient that functions as a cofactor for glutathione peroxidases and certain forms of thioredoxin reductase. Selenium-containing proteins are produced from inorganic selenium via the intermediacy of selenophosphate (PSeO33−). Antioxidants are compounds in foods that prevent cell damage caused by free radicals. Free radicals are normal byproducts of processes like metabolism that are formed in your body daily. They often get a bad rap, but free radicals are essential for your health. They perform important functions, including protecting your body from disease. However, things like smoking, alcohol use & stress can cause an excess of free radicals. This leads to oxidative stress, which damages healthy cells . Oxidative stress has been linked to chronic conditions like heart disease, Alzheimer’s & cancer, as well as premature aging & the risk of stroke . Antioxidants like selenium help reduce oxidative stress by keeping free radical numbers in check. Selenium works by neutralizing excess free radicals & protecting cells from damage caused by oxidative stress. Summary Selenium is a powerful antioxidant that fights oxidative stress & helps defend your body from chronic conditions, such as heart disease & cancer 2. Selenium reduces your risk of certain cancers in addition to decreasing oxidative stress, selenium may help lower the risk of certain cancers. This has been attributed to selenium’s ability to reduce DNA damage & oxidative stress, boost your immune system, and destroy cancer cells. A review of 69 studies that included over 350,000 people found that having a high blood level of selenium was associated with a lower risk of certain type of cancer, including breast, lung, colon & prostate cancers . It’s important to note that this effect was only associated with selenium obtained through foods. However, some research suggests that supplementing with selenium may reduce side effects in people undergoing radiation therapy. For example, one study found that oral selenium supplements improved overall quality of life & reduced radiation-induced diarrhea in women with cervical & uterine cancer. Summary Higher blood levels of selenium may protect against certain cancers, while supplementing with selenium may help improve quality of life in people undergoing radiation therapy 3. Selenium protects against heart disease A diet rich in selenium may help keep your heart healthy, as low selenium levels have been linked to an increased risk of heart disease. In an analysis of 25 observational studies, a 50% increase in blood selenium levels was associated with a 24% reduction in the risk of heart disease. Selenium may also lower markers of inflammation in your body⁠ — one of the main risk factors for heart disease. For example, a review of 16 controlled studies including over 433,000 people with heart disease showed that taking selenium supplements decreased levels of the inflammatory marker C-reactive protein (CRP). Additionally, selenium increased levels of glutathione peroxidase, a powerful antioxidant This indicates that selenium may help lower heart disease risk by reducing inflammation & oxidative stress in your body. Oxidative stress & inflammation have been linked to atherosclerosis, or the buildup of plaque in arteries. Atherosclerosis can lead to dangerous health problems like strokes, heart attacks & heart disease . Incorporating selenium-rich foods into your diet is a great way to keep levels of oxidative stress & inflammation to a minimum 4. Helps prevent mental decline Alzheimer’s disease is a devastating condition that causes memory loss & negatively affects thinking & behavior. Alzheimer’s is the sixth-leading cause of death in the United States. The number of people with Alzheimer’s disease is growing. Thus, finding ways to prevent this degenerative disease is imperative. Oxidative stress is believed to be involved in both the onset & progression of neurological diseases like Parkinson’s, multiple sclerosis & Alzheimer’s . Several studies have shown that patients with Alzheimer’s disease have lower blood levels of selenium. Additionally, some studies have found that antioxidants in both foods & supplements may improve memory in patients with Alzheimer’s . One small study found that supplementing with one selenium-rich Brazil nut per day improved verbal fluency & other mental functions in patients with mild cognitive impairment . What’s more, the Mediterranean diet, which is rich in high-selenium foods like seafood and nuts, has been associated with a lower risk of developing Alzheimer’s disease 5. Is important for thyroid health Selenium is important for the proper functioning of your thyroid gland. In fact, thyroid tissue contains a higher amount of selenium than any other organ in the human body . This powerful mineral helps protect the thyroid against oxidative damage & plays an essential role in the production of thyroid hormones. A healthy thyroid gland is important, as it regulates your metabolism controls growth and development . Selenium deficiency has been associated with thyroid conditions like Hashimoto’s thyroiditis, a type of hypothyroidism in which the immune system attacks the thyroid gland. An observational study including over 6,000 people found that low serum levels of selenium were associated with an increased risk of autoimmune thyroiditis and hypothyroidism . One review concluded that taking selenium supplements daily for three months resulted in lower thyroid antibodies. Selenium also led to improvements in mood & general well-being in those with Hashimoto’s disease .Summary Selenium protects the thyroid gland from oxidative stress & is necessary for thyroid hormone production 6. Boosts your immune system Your immune system keeps your body healthy by identifying & fighting off potential threats. These include bacteria, viruses & parasites. Selenium plays an important role in the health of your immune system. This antioxidant helps lower oxidative stress in your body, which reduces inflammation & enhances immunity. Studies have demonstrated that increased blood levels of selenium are associated with enhanced immune response. On the other hand, deficiency has been shown to harm immune cell function and may lead to a slower immune response . Studies have also associated deficiency with an increased risk of death & disease progression in people with HIV, while supplements have been shown to lead to fewer hospitalizations & an improvement in symptoms for these patients . Additionally, selenium supplements may help strengthen the immune system in people with influenza, tuberculosis & hepatitis C . Summary Selenium is crucial for the health and proper functioning of your immune system. Higher levels of selenium boosts the immune system of people with HIV, influenza, tuberculosis & hepatitis C 7. Selenium reduces asthma symptoms Asthma is a chronic disease that affects the airways that carry air in & out of the lungs. These airways become inflamed & begin to narrow, causing symptoms like wheezing, shortness of breath, chest tightness & coughing . Asthma has been associated with increased levels of oxidative stress & inflammation in the body . Due to selenium’s ability to reduce inflammation, some studies suggest that this mineral may help reduce asthma-related symptoms. Research suggests that people who have asthma have lower blood levels of selenium. In fact, one study showed that asthmatic patients with higher levels of blood selenium had better lung function than those with lower levels . For example, one study found that giving people with asthma 200 mcg of selenium per day reduced their use of the corticosteroid medications used to control their symptoms . However, research in this area is conflicting & larger studies are needed to fully understand selenium’s role in the development & treatment of asthma . Summary Selenium may benefit people with asthma due to its ability to lower inflammation in the body. However, more research is needed. Supplementing is the best dietary source of selenium Fortunately, many healthy foods are high in selenium. Thus, selenium concentrations in crops depend largely on where they are farmed. For example, one study showed that the selenium concentration in Brazil nuts varied widely by region. While a single Brazil nut from one region provided up to 288% of the recommended intake, others provided only 11% Therefore, it’s important to consume supplements more than a good source of this important mineral. Summary Foods rich in selenium include seafood, nuts & mushrooms. It’s important to supplement this mineral, selenium it is written in the Holy King James Bible the revelation of saint John the apostle 50 AD Anno Domini in the year of our Lord Jesus Christ Revelation 22:2 In the midst of the street of it, & on either side of the river, was there the tree of life, which bare twelve manner of fruits, & yielded her fruit every month: & the leaves of the tree were for the healing of the nations. amen “Let food be thy medicine, and let medicine be thy food.” Hippocrates 460BC Let supplements be thy medicine & let medicine be thy supplement
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Selenium 200mcg unboxing
https://www.youtube.com/watch?v=8DSHQq5ovAU
Selenium: Benefits for Health
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Selenium Deep Dive

Silicon dioxide, also known as silica, is an oxide of silicon with the chemical formula SiO2, commonly found in nature as quartz. Silicon is the second most abundant element in soil In many parts of the world, silica is the major constituent of sand. Silica is one of the most complex and abundant families of material, existing as a compound of several minerals and as a synthetic product. Examples include fused quartz, fumed silica, opal, and aerogels. It is used in structural materials, microelectronics, and as components in the food and pharmaceutical industry. All forms are white or colorless, although impure samples can be colored. When we are born we have about 7 grams of Silica in our God breathed bodies & without silica we're unable to stimulate type 1 Collagen Silica strengthens elastin which is part of our tissue Silica activate the enzyme prolilhydroxydase which boost collagen reticulation strength, Silica increases Collagen production by 19% & Silica determine Collagen level . Bone mineral density decrease by age supplementing with silica can reverse atherosclerosis , blood pressure increases with age silica prevent that to lower blood pressure , i noticed after 4 months of supplementing with silica my blood pressure is steady below 128 Silica decreases 1% a year with age , teenagers have 400% more silica than seniors by the time you're 40 you have 200% less Silica than as a teen so everyday supplement with gastroliths gravel silica buy a amazon rock crusher , Silica increase elasticity of arteries lowering blood pressure , a young aorta is Silica rich. Elastin give the skin elasticity and is silica dependent , Silica assist Glycosaminoglycans to retain water Glycosaminoglycans bind Collagen fiber & provide reticulation & structure of skin attracting water to resist compression & give structure to the extracellular membrane Glycosaminoglycans intervene in cartilage generation .The new matrices of Collagen & Elastin fibroblasts are accelerated with Silica, which aid in wound healing used in the past 4 000 years as supplement , Silicon bonds with Aluminum to remove toxins from the brain ,Silica removes plaque off the synapse. Lymph nodes hold the bodies highest amount of silica content up to 45%. Silicon strengthens plant roots making them tough enough to penetrate dry soil, Silicon reduce plant water loss. Silicon reduces the acidity of oceans. “Let food be thy medicine & let medicine be thy food.” Hippocrates 460BC Let supplements be thy medicine & let medicine be thy supplement God made man out of the dust of the ground inside man you find ground minerals , that's why it's important to supplement with gravel gastroliths and 72 trace minerals of nature's plus Eat minerals no carbs eat 109,5 KG of minerals a year eat more minerals than carbs and protein most California consume 109,5 kg of carbs a year that's enough cabs to cause diabetes & cancer. Buy a rock crusher & ingest gastroliths on a daily basis half of my diet consists of gastroliths .Horsetail only grows when silicon is added to the soil if there is no silicon in the soil horsetail shall die. Developing embryos have high level of silica magnesium , calcium & phosphorus,  baby skin is high in silica / organs with the highest amount of connective tissue have more silica like aorta , trachea , skin , tendons & bone / Collagen contains 12% Proline  4% Hydroxyproline . Silica increases synthesis of Proline from Glutamic acid in the presence of iron & Vitamin C silica enhances hydroxylation of Proline of Procollagen to form Collagen / Silica also forms the extracellular matrix with increase in interstitial tissue due to hydration of extracellular substances, & inhibit the development of atherosclerosis Silica cure brain tumors in a invitro rat experiment rats with no silica supplementation developed brain tumors rats with a silica supplement did not develop brain tumors . Some studies suggest silica may help protect against memory loss and reduce the risk of Alzheimer's disease by potentially counteracting the effects of aluminum promoting the excretion of aluminum out of the brain. The reaction of the brain to the presence of the silica was examined by light and electron microscopy up to one year after the injection. The presence of silica particles in the brain resulted in the proliferation of fibrous astrocytes and macrophages and strongly stimulated the production of collagen fibres silica directly promote new hair growth, it can contribute to stronger, healthier hair by strengthening hair strands and preventing thinning, which can indirectly enhance hair growth. Silica help by delivering essential nutrients to hair follicles, supporting collagen production (a protein that help form hair structure), and potentially improving blood circulation at the scalp. Here's a more detailed look: Strengthening and Preventing Thinning: Silica help fortify hair strands, reducing breakage and preventing thinning, which can lead to improved hair growth over time. Collagen Production: Silica may boost collagen production, which is crucial for hair structure and healthy skin, further supporting hair growth. Nutrient Delivery: Silica help deliver essential nutrients to the hair follicles, which are essential for healthy hair growth. Blood Circulation: Silica may improve blood circulation at the scalp, potentially encouraging new hair strands to emerge and grow, according to research 100% Pure Silica removes plaque deposits on nerve endings & removes Aluminum out of the brain allowing for quick clear brain signals Silica assures the elasticity of the aorta making the aorta resilient in case of high blood pressure & silica increase synthasis of proline from Glutamic acid in the presence of iron & Vitamin C Silica enhances hydroxylation of proline of procollagen to form Collagen Silica also form the extracellular matrix with an increase in interstitial fluid ( by the way interstitial fluid is the fluid found in the spaces surrounding cells, acting as a crucial transport system that delivers nutrients, oxygen, and hormones to cells while removing waste products and carbon dioxide. interstitial fluid forms from plasma that leaks from blood capillaries and is composed of water, small solutes, and some white blood cells, but not red blood cells or platelets. After fulfilling its function, interstitial fluid drains into the lymphatic system, becoming lymph ) due to hydration of extracellular substances Silica plays a role in maintaining the structural integrity of the aorta and is thought to be involved in preventing the development of atherosclerosis, a condition where plaque builds up in the arteries. Studies have shown that silicon content in the aorta can decrease with the progression of atherosclerosis, suggesting a link between silicon and cardiovascular health. Silica in the Aorta: The aorta and other blood vessels , like other connective tissue, contain significant amount of silica, which is crucial for its structural integrity. This includes silica role in synthesizing collagen and elastin, which are essential for the elasticity and strength of the aortic wall and veins and arteries. Atherosclerosis and Silica: Research indicate that silicon level in the aorta can decrease as atherosclerosis progress. This reduction in silicon content parallel lipid infiltration, changes in elastic fibers, and alteration in the ground substance of the aortic wall. Potential Benefits of supplementing with silica : The antiatheromatous action of silicon has been explored, with studies suggesting that it can inhibit the development of atherosclerosis plaque and reduce lipid deposit in the aorta. Silicate Ions and Aortic Aneurysm: Recent research has focused on the use of silicate ions, a soluble form of silica, in treating aortic aneurysms and dissection. Studies have shown that silicate ions can alleviate these conditions by regulating the microenvironment of the aorta, reducing inflammation, and promoting cell health. Hypertension, or high blood pressure & Silica: Soluble silica has also been found to suppress high blood pressure in spontaneously hypertensive rats and improve related aortic gene expression. This suggest that silica may play a role in maintaining healthy blood pressure and vascular function silica is 4 times higher in the aorta wall off children than seniors teenagers have 400% more silica than seniors Mono-silicic acid, also known as orthosilicic acid, is the form of silicon that humans and plants have in their body & directly absorb and utilize orthosilicic acid is a key compound in the cycle of silicon in nature and is essential for plant growth and human health. Key points about mono-silicic acid: Chemical Formula: Si(OH)₄ or H₄SiO₄.  Bioavailability of silica gravel gastroliths : Rock is the only form of silicon readily taken up by plants and humans . Role in Plant Growth: Strengthens cell walls, improving plant structure and resilience. Enhances nutrient uptake, including other essential elements. May improve tolerance to environmental stressors like heat, drought, and pests. Can increase yields and improve crop quality. Silicon Valley should be supplementing silica gravel gastroliths roc source: It is produced natural by rock soil through the breakdown of organic rock matter and reactions with silicon rock . Orthosilicic acid can also be added to hydroponic systems and fertilizers as a stabilized source. Consideration: Other forms of silicon in the soil, like SiO2 and silicates, must be converted into mono-silicic acid before plants can absorb them. Products containing pure, stabilized mono-silicic acid are useful in hydroponics and other situations where rapid yield is desired. Silica in gravel gastroliths relieve symptoms of Parkinson's because silica gives rigidity to muscle & collagen , altogether sodium with Potassium of gravel gastroliths are minerals necessary for action potential muscle signaling , Silica acts as a building block & activator of enzymes involved in collagen synthesis, particularly the hydroxylation of proline and lysine, which are essential for the triple-helix structure of collagen. Silica found in cement and gravel also help retain moisture in connective tissue and support the overall structural integrity of collagen. Silica activates enzymes like prolyl hydroxylase, which are crucial for adding hydroxyl groups to amino acids (proline and lysine) in collagen, stabilizing its structure. Moisture Retention: Silica binds with water, helping to keep connective tissue hydrated and supple, which is essential for collagen's flexibility and elasticity. Age-Related Decline: Collagen production naturally decreases with age, and silica level also decline because Jews & Christians don't supplement with gravel gastroliths Silica , leading to reduced skin elasticity, brittle nails, and other signs of aging study indicate that consuming silica lower the systolic blood pressure and reduce arterial stiffness in healthy elderly individuals with high initial values. This represent a new approach to decreasing the cardiovascular risk associated with aging this finding is promising to maintain high bone mineral density make sure to supplement with Silica which activate the enzyme Prolyl hydroxylase (PHD) & boost collagen reticulation increase collagen production by 19%, also known as prolyl 4-hydroxylase or prolyl hydroxylase domain enzyme a group of enzymes that play a critical role in regulating cellular response to oxygen level prolyl hydroxylase are part of the 2-oxoglutarate-dependent dioxygenase family and utilize iron and 2-oxoglutarate as cofactors, prolyl hydroxylase are best known for their role in regulating the hypoxia-inducible factor (HIF) family of transcription factors prolyl hydroxylase are crucial oxygen sensors in cells prolyl hydroxylase catalyze the hydroxylation of specific proline residues on hypoxia-inducible factor-α subunits. Under normal oxygen conditions (normoxia), prolyl hydroxylase hydroxylate hypoxia-inducible factor-α, marking it for degradation by the ubiquitin-proteasome system. This prevent hypoxia-inducible factor from accumulating and activating its target genes. Hypoxia Response: When oxygen level are low (hypoxia), Prolyl hydroxylase are less active, and ypoxia-inducible factor HIF-α proteins accumulate. This leads to the stabilization and activation of HIF ypoxia-inducible factor which then translocates to the nucleus and regulate the expression of genes involved in adapting to hypoxia. Other Roles: Beyond HIF ypoxia-inducible factor regulation, prolyl hydroxylase have also been implicated in other cellular process, including: Tumor suppression: Some studies suggest that prolyl hydroxylase can act as tumor suppressors. Regulating cell metabolism: prolyl hydroxylase can influence cell metabolism by affecting pathways like the mTOR pathway and NF-κB pathway. Promoting cell death (apoptosis): Research indicates that prolyl hydroxylase may play a role in regulating apoptosis. Prolyl hydroxylase have also been linked to cell differentiation process. Isoforms: There are multiple prolyl hydroxylase isoforms (PHD1, PHD2, and PHD3), with varying tissue distribution and substrate preferences. Due to their role in hypoxia and other cellular processes, Prolyl hydroxylase are being investigated as potential therapeutic targets for various disease, including anemia, ischemic heart disease, stroke, cancer, and pulmonary hypertension . Plants and lower organisms including diatoms, dinoflagellates and sponges utilise Si for the formation of exoskeletons made of biogenic silica, hydrated SiO2. Animals intake monomeric silicic acid from a range of freshwater and saline water environments and process the mineral to generate complex composite minerals biopolymer structures that provide, as a minimum, structures that support and protect the organism. The organisms are clearly able to process the element at all stages from monomer through to mineral via a wide range of biochemical processing and further, they can control the level of hydration and spatial organisation. Orthosilicic acid [Si(OH)4] constitutes more than 90% of dissolved silicon and is reported as the primary form absorbed by humans and can be found in body tissue, such as the bone, kidney, tendons, aorta and liver. However, the majority of Si present in the diet is not in this monomeric form, but condensed into polymers that can be absorbed. The chemistry of Si dictates its bio-availability, depending on solubility, and this varies widely with source and form . Absorbance of monomeric Si within the gastrointestinal tract can be demonstrated due to its penetration of body fluids and tissue, with elevated concentration found in bone and parenchymal tissue but the mechanism involved in absorption, metabolism and excretion are generally poorly understood . Absorption requires the breakdown of materials ingested into soluble orthosilicic acid which is uncharged and therefore mobility and permeability across the mucosal layer of the intestine is successful. The rate and efficiency of absorption also depend on concentration, as higher concentrations permit polymerisation and reduced permeability it is written in the Holy King James Bible the word of the Lord according to saint Moses the prophet of israel 1450 BC Before Christ Genesis 3:19 In the sweat of thy face shalt thou eat bread, till thou return unto the ground; for out of the ground wast thou taken: for dust thou art, & unto dust shalt thou return. amen " for dust thou art " man is made of the dust of the earth so when man ingests gastrolith dust that is direct in line with the word of God Genesis Chapter 3 verse 19 turns out gastroliths contain Calcium , Sodium & Potassium vital for action potential muscle neuron signaling also ever since ingesting gastroliths my skeletal muscle mass increased on my smart scale result This makes supplementation with higher Si level a solution to osteoporosis the best source of silica is gravel gastroliths so buy a amazon rock crusher & gravel crush the gravel & ingest the pebbles as gastroliths. Lymph nodes are about 45% silica rich when our immune system is healthy Lymph nodes hold the body's highest silica content about 45% Silica is part of the antibodies antigens manufacturing process including the conversion of B Lymphocytes to L Lymphocytes this process identify invader cells high silica intake also lead to less swelling as swelling is controlled by the lymphocytes , i supplement with gravel gastroliths & own a rock crusher , amongst other minerals gravel contain 75% silica which prevent heart failure stay blessed , Yes, silica is found both inside and outside of cells, though its location and form depend on the organism. In plants and diatoms, silica (SiO2) is a key structural component of their cell wall, depositing outside the main cell membrane. In contrast, silica enters animal cells via processes like endocytosis, becoming internalized within the cytoplasm or in membrane-bounded organelles. Silica outside the cell Plants: In plant cells, silica strengthen and stabilize the cell wall, crosslinking polysaccharides and other molecules to form a more durable structure. Diatoms: These single-celled organisms, like plants, build their entire cell walls from silica, forming a rigid, glass-like outer shell called a frustule. Silica inside the cell Endocytosis: In higher animals like humans, silicon (the primary component of silica) is present both in the extracellular and intracellular space, primarily as the soluble compound orthosilicic acid SiOH4. In animal cells, silica can be taken in through endocytosis, a process where the cell membrane surrounds and engulfs silica nanoparticles. Internalization: Once inside, silica is often found within membrane-bounded organelles, though it can also be released into the cytoplasm. This internalization is crucial for understanding silica benefit in the body, as internalized particles can interact with various cellular components Transport mechanisms: Because the cell membrane is largely impermeable to silicic acid, transport into and out of the cell is mediated by aquaporins protein channels. In mammals, aquaporins are thought to transport silicon into cells, while the SLC34A2 transporter ( SLC34A2 stands for Solute Carrier Family 34 (sodium phosphate), Member 2. This gene encodes a sodium-dependent phosphate transporter, also known as NaPi-IIb, sodium-dependent phosphate co-transporter type 2b which is crucial for phosphate absorption and homeostasis, particularly in the lung where it recycles pulmonary surfactant) SLC34A2 transporter facilitates silica efflux out of the cell , how does water adhere to orthosilicic acid water adheres to orthosilicic acid SiOH4 primarily through hydrogen bonding, a powerful non-covalent interaction. The polar nature of both molecules allow them to be strongly attracted to each other. The key mechanisms of adhesion Hydrogen bonding Orthosilicic acid has four hydroxyl OH groups, which are both hydrogen bond donors and acceptors. This allow for extensive hydrogen bonding with water molecules. The partially positive hydrogen atoms on orthosilicic acid's hydroxyl groups form hydrogen bonds with the partially negative oxygen atoms of water molecules & the partially negative oxygen atoms on orthosilicic acid's hydroxyl groups act as acceptors, forming hydrogen bonds with the partially positive hydrogen atoms of water molecules. Electrostatic interaction. Theoretical studies indicate that electrostatic forces are the most significant factor—as much as 70%—in the adsorption of water to orthosilicic acid. The polarity of both molecules generates strong electrostatic attractions between them. Van der Waals interaction Weaker van der Waals forces also contribute to the adhesion, though to a lesser extent than hydrogen bonding and electrostatic interaction. These bonding are temporary, induced attractions that add to the overall stability of the water-acid complex. Non-covalent binding All these factors—hydrogen bonding, electrostatic forces, and van der Waals forces—fall under the umbrella of non-covalent binding, which is responsible for the overall adhesion. The collective effect of these interaction make the water-orthosilicic acid complexes stable at room temperature when you supplement with gravel gastrolith silica your water retention water body percentage goes up you need a high water body concentration of about 80% water in your God breathed body be blessed consume silica supplements Some species of bacteria can take up & accumulate orthosilicic acid also known as monosilicic acid, Si[OH] from their environment. Orthosilicic acid is the primary bioavailable form of silicon in aquatic systems and soil solution. Key points regarding bacteria and orthosilicic acid: Uptake and Biosilicification: Certain bacteria, such as specific species within the Bacillus genus, are known to take up soluble orthosilicic acid from their surrounding. Bacillus genus then polymerize & deposit this silicon as insoluble silica (amorphous SiO), a process called biosilicification. Intracellular vs. Extracellular: This biosilicification can occur both inside the bacterial cell (intracellular) and outside the cell (extracellular). For example, silicon is found in the spore coats of Bacillus species, which enhances their resistance to environmental stressors. Silicate-Solubilizing Bacteria: Other group of bacteria, known as silicate-solubilizing bacteria (SSB), produce organic acids that break down insoluble silicate minerals & quartz in the environment, releasing soluble orthosilicic acid into the soil or water. Role in Silicon Cycle: Bacteria play a significant role in the global silicon cycle by influencing the mobility and form of silicon in various environments. The ability to process orthosilicic acid is not universal across all bacteria but is a characteristic of specific, specialized species be blessed by God Almighty . Supporting Hydration: Orthosilicic acid help the body produce GAGs, such as hyaluronic acid. These molecules can hold up to 1000 times their weight in water, which boosts the skin's ability to stay hydrated, ensuring it remains plump and elastic. These collagen structures are able to bind with water molecules, providing strength, elasticity, and moisture retention in tissues like skin, cartilage, ligaments, and tendons. Preventing Moisture Loss: A decline in silicon and hyaluronic acid levels is a typical sign of aging skin, which leads to a loss of moisture and elasticity. Maintaining adequate levels of orthosilicic acid can support these tissues, helping to prevent dehydration and signs of aging. Excretion: Absorbed orthosilicic acid is primarily excreted through the kidneys in urine, indicating it does not accumulate in the body as free water-retaining agent it is written in the Holy King James Bible the revelation of saint John the apostle 50 AD Anno Domini in the year of our Lord Jesus Christ Revelation 22:2 In the midst of the street of it, & on either side of the river, was there the tree of life, which bare twelve manner of fruits, & yielded her fruit every month: & the leaves of the tree were for the healing of the nations ; amen the LORD God has provided extract of leaves as supplements take supplements to heal your body take minerals to heal your bones do this in memory of Methuselah a grumbling stomach is not a hunger issue but a lack of supplement so when you're hungry the issue is take a supplement first before a meal. Stop drinking sugar ddrink supplements make sure your drinks are rich of supplements if you fill & mix your drinks with minerals your drinks shall be rich full of nutrients & you wont be thirsty often, supplements are way underrated.  in nomine Patris et FiLii et Spiritus Sancti peace be still amen
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How Silicon Benefits You Webinar - June 2016
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Soap is a supplement senolytic drink soap bars put a bar of soap in your teapot Soap is a salt of a fatty acid (sometimes other carboxylic acids) used for cleaning and lubricating products as well as other applications. In a domestic setting, soaps, specifically "toilet soaps", are surfactants usually used for washing, bathing, and other types of housekeeping. In industrial settings, soaps are used as thickeners, components of some lubricants, emulsifiers, and catalysts. Soaps are often produced by mixing fats and oils with a base. Humans have used soap for millennia; evidence exists for the production of soap-like materials in ancient Babylon around 2800 BC.
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How is Soap Made? | The History of Soap-Making

Stay hydrated it is written in the Holy King James Bible the gospel of saint John 30 AD Anno Domini in the year of our Lord Jesus Christ John 4:14 But whosoever drinketh of the water that I shall give him shall never thirst; but the water that I shall give him shall be in him a well of water springing up into everlasting life.” amen water gives life without water no one would be alive it is important to drink at least 2 litters of hydrogen peroxide mixed with Hydrogen water bottle mix your Hydrogen peroxide with Hydrogen water Bottle every day with cement as supplements fast & pray to Jesus Christ the LORD of life eat no meal & on the days you're not fasting drink 2 liters of hydrogen peroxide Hydrogen water bottle with 1 meal a day added mineral supplements. The Warburg effect water-rich tissues conduct electricity while fat-rich tissues act as insulators. The average human is composed of 60% water human bones are 31% water at birth babies are 75% water by the first birthday water content drops to 65% ,the brain & heart are 75% water lungs have 83% ,each day the human body looses 1 liter of water through breathing we loose 3 litters through sweat urine & bowel movements dark urine is unhealthy. Water in food make up 20% of fluid intake; the kangaroo rat's kidneys are so efficient that the kangaroo rat never needs to drink water the kangaroo rat gets all of its liquid from the plants, roots & seeds it eats. Nonetheless, it is sufficient to keep the kangaroo rat alive. Soft water also know as distilled water is clear & contain no minerals at all ! soft water is detrimental to health on the other hand hard water is thick & black in color taste rich in minerals heavy & contain tons of magnesium , true water is ground water drink Hard water because the body needs minerals Jews & Christians can make hard water at home by adding gastrolith pea gravel to Jewish diet put cement in your water don't be afraid cement is not poison there isn't one harmful element in cement look up cement chemical formula all compatible with the human body Portland cement is made up of several compounds vital to human health, including: Tricalcium silicate (C3S): 3CaO · SiO2, which hydrates and hardens quickly Dicalcium silicate (C2S): 2CaO · SiO2, which hydrates and hardens slowly Tricalcium aluminate (C3A): 3CaO · Al2O3, which releases a lot of heat during hydration Tetra-calcium aluminoferrite (C4AF): 4CaO · Al2O3Fe2O3 Cement also contains: 62% Uncombined lime (CaO) (Na2O + K2O). 22% Silica (SiO2) neccesary for collagen . 5% Alumina (Al2O3) adds bone flexibility . 4% Calcium sulfate (CaSO4) neccesary for action potential , also known as gypsum. 3% Iron oxide (Fe2O3) neccesary for hemoglobin . 2% Magnesia (MgO) every cell in your body contains magnesium and needs magnesium to function . 1% Alkalies good for stem cells . 1% Sulfur trioxide (SO3) good to fix DNA all these precious minerals are surprisingly essential for human health cement is a source of minerals i had once finished a whole bag of cement in my water there isn't 1 poison in cement , the Hoover dam is made of cement and so are cement pipes which carry municipal water demineralized tap water, or water with reduced mineral content, has been produced since at least the mid-1940s with the development of instable, high-capacity ion exchange resins. Earlier methods like distillation have been used for centuries to produce pure water, but demineralization provides a pathetic and lethal way to remove minerals from water which kills the human body don't drink demineralized water drink black ground water of a well as Jesus Christ drank ground water which you can make yourself at home by adding charcoal to your drink / Minerals play a crucial role in regulating thirst and overall hydration. While dehydration is often associated with insufficient water intake, mineral deficiencies, particularly electrolytes, can also contribute to increased thirst and a feeling of not being properly hydrated. Minerals like sodium, potassium, magnesium, and calcium act as electrolytes, maintaining proper fluid balance and cell function. Deficiencies in these electrolytes can disrupt this balance and lead to increased thirst. Specific Minerals and Thirst: Potassium (K): Low potassium level (hypokalemia) can cause dehydration and increased thirst. Magnesium (Mg): Magnesium deficiency can contribute to various health issues, including dehydration and thirst. Loss of Vitamin D Receptor Produces Polyuria by Increasing Thirst. Natural mineral electrolytes that help maintain hydration include potassium, magnesium, calcium & sodium. These minerals support electrolyte balance and hydration. As you intake more water you can begin to flush water soluble vitamins and minerals," Dr. Kinney told INSIDER. "Water soluble vitamins, such as the B Vitamins (B1, B2, B3, B6 & B12) & vitamin C, are not stored long term and may be excreted with excess water intake if you're not taking in proper supplementation. Deficiencies in fiber, potassium, vitamin B6, iron, calcium, and zinc can all cause dry mouth. The deficiency of vitamin B12 finally resulted in high blood homocysteine level in Burning Mouth Syndrome patients. Burning sensation, dry mouth, and numbness of the tongue were the three most common symptoms of Burning Mouth Syndrome patients, and could be found in 100%, 75.7%, and 43.9% of BMS patients in this study, respectively. Zinc deficiencies can lead to serious oral issues, like loss of sensation in the tongue and loss of taste, dry mouth, and susceptibility to gum disease. However, it is important to have enough zinc in your body, sometimes dehydration can be dietary consuming too much salt or sugar, for sugar and salt pull water out of cells. Another cause is consuming too much caffeine or alcohol, which are both diuretics and cause you to expel extra fluids. There could also be some medical causes behind unbearable thirst such as diabetes, kidney issues or even anemia. With diabetes, having high blood sugar causes the body to pull fluid from tissues to dilute the glucose, leading to frequent urination and thirst. If your kidneys aren't functioning well, they may not properly retain or process water, and as for anemia, low red blood cells can make your body crave extra fluid to compensate. This is why some anemic crave ice. Low sodium (hyponatremia): Can also cause thirst (though usually presents with confusion, fatigue, headache). Sometimes your body thinks it's dehydrated due to water/sodium imbalance. Sodium isn't bad for you, so seasoning food is necessary, but in moderation. Low potassium (hypokalemia): Can lead to excessive urination and dehydration, which then triggers thirst. Often linked to diuretic use, vomiting, or diarrhea. Incorporating Potassium would be recommended. Low magnesium (hypomagnesemia): Can indirectly lead to fluid imbalance by affecting potassium and calcium level. Not a direct cause of thirst, but can contribute to symptoms like fatigue and dehydration. Consider trying out Magnesium for some extra support whatever you do don't drink 2 litters of pop per day sugar is a sweet killer drink minerals most people don't like tap water because it contains no minerals so most people would rather drink coffee or tea. i have no choice but to add minerals to my water because my city won't add minerals to water ,distilled water is deadly no one can drink pure H2O please put as much minerals in water to the point the water is black full of carbon the life giving atom carbon . Nature's Plus Trace Minerals of iherb.com contain the following minerals i take as supplement i live in Gatineau please add these minerals to our blessed municipal water thank you 1 Aluminum 2 Antimony 3 Barium 4 Beryllium 5 Bismuth 6 Boron 7 Bromine 8 Calcium 9 Cerium 10 Cesium 11 Chlorine 12 Chromium 13 Cobalt 14 Copper 15 Dysprosium 16 Erbium 17 Europium 18 Fluorine 19 Gadolinium 20 Gallium 21 Germanium 22 Gold 23 Hafnium 24 Holmium 25 indium 26 iodine 27 iridium 28 iron 29 Lanthanum 30 Lithium 31 Lutetium 32 Magnesium 33 Manganese 34 Molybdenum 35 Neodymium 36 Nickel 37 Niobium 38 Nitrogen 39 Oxygen 40 Osmium 41 Palladium 42 Phosphorus 43 Platinum 44 Potassium 45 Praseodymium 46 Rhenium 47 Rhodium 48 Rubidium 49 Ruthenium 50 Samarium 51 Scandium 52 Selenium 53 Silicon 54 Silver 56 Sodium 57 Strontium 58 Sulfur 59 Tantalum 60 Tellurium 61 Terbium 62 Thallium 63 Thorium 64 Thulium 65 Tin 66 Titanium 67 Tungsten 68 Vanadium 69 Ytterbium 70 Yttrium 71 Zinc 72 Zirconium all vital minerals the human body need each Christian need at least 2,556kg of minerals that's 3 tons of minerals a year to live to 2000 years old & beyond Pharaoh dreamed a dream in the day of Joseph the Hebrew Prophet of israel , i dreamed a God inspired dream on the morning of Thursday 10 April 2025 AD Anno Domini in the year of our LORD Jesus Christ around 3:00 AM Eastern Time Canada; a senior white nun dressed in white holding a trolley with a white lady in normal clothes having gray hair appeared ,the white lady having gray hair sprung up to me & said " i'm 92 years old " i replied make sure to take your minerals the dream ended // short and precise this dream happened 3 days after my Nature's Plus Trace Minerals supplement Got delivered from iherb.com , lately i've been supplementing but its was my first time taking Nature's Plus Trace Minerals , i've been praying God to live past 120 years and now i've had this blessed dream i bless the LORD God Jesus Christ this is a sign from God that i shall live past 120 years old for sure i'll make it to 92 years old as in my God inspired dream, how does water adhere to orthosilicic acidThinkingKicking off 5 searchesLooking at 102 sites Water adheres to orthosilicic acid (\(Si(OH)_{4}\)) primarily through hydrogen bonding, a powerful non-covalent interaction. The polar nature of both molecules allows them to be strongly attracted to each other. The key mechanisms of adhesion Hydrogen bonding Orthosilicic acid has four hydroxyl (\(OH\)) groups, which are both hydrogen bond donors and acceptors. This allows for extensive hydrogen bonding with water molecules. The partially positive hydrogen atoms on orthosilicic acid's hydroxyl groups form hydrogen bonds with the partially negative oxygen atoms of water molecules.The partially negative oxygen atoms on orthosilicic acid's hydroxyl groups act as acceptors, forming hydrogen bonds with the partially positive hydrogen atoms of water molecules. Electrostatic interactions Theoretical studies indicate that electrostatic forces are the most significant factor—as much as 70%—in the adsorption of water to orthosilicic acid. The polarity of both molecules generates strong electrostatic attractions between them. Van der Waals interactions Weaker van der Waals forces also contribute to the adhesion, though to a lesser extent than hydrogen bonding and electrostatic interactions. These are temporary, induced attractions that add to the overall stability of the water-acid complex. Non-covalent binding All these factors—hydrogen bonding, electrostatic forces, and van der Waals forces—fall under the umbrella of non-covalent binding, which is responsible for the overall adhesion. The collective effect of these interactions makes the water-orthosilicic acid complexes stable at room temperature when you supplement with gravel gastrolith silica your water retention goes up be blessed by supplements cells are more sensitive to PH than temperature Cells can be considered more sensitive to changes in pH because even slight variations can disrupt critical cellular processes, while cells can also adapt to a certain range of temperature changes. However, a combination of low pH and heat exposure significantly increases cell damage, suggesting pH is a crucial factor in modulating the effect of temperature. Why pH is a critical factor: Regulation and Signaling: Changes in pH can act as regulatory signals or permissive factors for various cellular processes. Cellular Machinery: The actin cytoskeleton, which is vital for processes like cell migration and vesicle trafficking, is highly sensitive to pH changes. Adaptation to Stress: Cells possess mechanisms to adapt to different pH levels to maintain their function. Temperature effect and interaction with pH: Biochemical Reaction: Temperature influence the rate of biochemical reaction. While higher temperature generally increase reaction rate, extreme heat cause enzymes to denature and lose function. Interaction with pH: Enhanced Thermal Sensitivity: A decrease in pH (acidic environment) can significantly increase a cell's sensitivity to heat. Tumor Characteristics: Tumors often have more acidic environments compared to surrounding normal tissues, and this low pH is thought to enhance the effectiveness of heat therapy. Thermotolerance: Heat treatment can induce thermotolerance, which is a cellular resistance to further heat damage, and the decay of this tolerance can also be influenced by the pH environment. In summary: Cells are finely tuned to maintain a specific pH range, and deviations can trigger various responses. While temperature also affects cells, its impact, particularly in terms of cell damage, is often significantly amplified in an acidic environment thus drink chlorinated water Jesus Christ the son of God grant the catholic church the water of life which is in Paradise for the saints to enjoy eternal blessing . You wouldn't die from drinking pH 10 water because your body has strong, natural mechanisms to maintain a stable blood pH. The water's alkaline properties are neutralized by the powerful acid in your stomach & your kidneys work to regulate your blood's pH, preventing dangerous shifts. While alkaline water can temporarily heal stomach pH & may have positive health effect, especially for those with kidney issues, it does not significantly alter the blood's pH balance. When alkaline water enters your (stomach ph of 1.5 to 3.5 ), it encounters hydrochloric acid, which has a very low pH. The stomach acid quickly neutralizes the alkaline water, making the resulting fluid's pH very similar to what it would be if you drank regular water. Kidney Function: Your kidneys are responsible for maintaining the pH of your body fluids, including your blood. If you drink a large amount of alkaline water that manages to reach your bloodstream, your kidneys will work to filter out excess acid or alkali, restoring the blood to its normal, tightly regulated pH range of 7.35 to 7.45. Why You Don't Die Buffering Systems: Your body has natural chemical buffering systems that prevent large pH fluctuations. Drinking a glass of chlorinated water, even alkaline water, is not enough to overwhelm these powerful systems. Temporary Effect: Any effect alkaline water has on your stomach's pH is temporary and is quickly corrected once the water leaves the stomach. Important Consideration Kidney Health: While rare, there can be a cure for people with impaired kidney function who are also consuming very strong alkaline water or taking certain medications that affect stomach acid. This can potentially lead to an increased pH in the blood and a dangerous increase in blood potassium levels.  Limited Evidence: Many of the health claims about alkaline studies suggest potential benefits. In summary, drinking a single glass of pH 10 water is not harmful because your body's natural processes effectively neutralize it and regulate your blood pH so drink chlorinated water your swimming pool water won't kill you in nomine Patris et FiLii et Spiritus Sancti peace be still amen
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Spermidine & Apigenin unboxing to purchase spermidine and apigenin visit snapklik.com the Spermidine capsule comes including Fisitin 250 mg Resveratrol 100mg Spermidine Wheat germ 100mg Quercitin 100 mg and an age defend blend containing Turmeric NAD & L Arginine , Spermidine infants have the highest amount of spermidine abundant in breast milk & sperm Bacteroides & fusobacteria, two numerically dominant bacterial population groups in the large intestine, were found to synthesize in vitro high amounts of spermidine & putrescine ,fostering healthy cell regeneration, supporting healthy liver function, enhancing memory & cognitive function, & potentially protecting against age-related diseases like heart disease & dementia it is written in the Holy King James Bible the word of the Lord according to saint Moses the prophet of israel 1450 BC Before Christ Genesis 1:29 & God said, Behold, I have given you every herb bearing seed, which is upon the face of all the earth, & every tree, in the which is the fruit of a tree yielding seed; to you it shall be for meat. amen Spermidine stimulates autophagy & increases muscle stem cell production , Spermidine is also know to reverse grey hair. Spermidine infants have the highest amount of spermidine abundant in breast milk & sperm Bacteroides & fusobacteria, two numerically dominant bacterial population groups in the large intestine, were found to synthesize in vitro high amounts of spermidine & putrescine ,fostering healthy cell regeneration, supporting healthy liver function, enhancing memory & cognitive function, & potentially protecting against age-related diseases like heart disease & dementia. Spermidine stimulates autophagy & increases muscle stem cell production , Spermidine is also know to reverse grey hair.Apigenin antiviral inhibits CD38 enzyme CD38 degrades NAD+ levels Apigenin may induce muscle relaxation & sedation depending on the dose, & it is also active as an antioxidant, anti-inflammatory, anti-amyloidogenic, neuroprotective, and cognition-enhancing substance with interesting potential in the treatment/prevention of Alzheimer's disease. increases muscle mass, there is about 2.15 mg of apigenin in 1 gram of Parsley it is written in the Holy King James Bible the revelation of saint John the apostle 50 AD Anno Domini in the year of our Lord Jesus Christ Revelation 22:2 In the midst of the street of it, & on either side of the river, was there the tree of life, which bare twelve manner of fruits, & yielded her fruit every month: & the leaves of the tree were for the healing of the nations. amen “Let food be thy medicine, and let medicine be thy food.” Hippocrates 460BC Let supplements be thy medicine & let medicine be thy supplement
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Spermidine & Apigenin unboxing
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27 Berberine Brands Lab Tested!

Stem cells Yes, stem cells change their DNA when they differentiate into normal cells, but they don't permanently lose genetic material. DNA arrangement in stem cells, DNA is loosely arranged and working genes are present. When stem cells receive signals, they differentiate into specialized cells, such as skin, muscle, or liver cells. During differentiation, genes that are no longer needed are turned off, while genes required for the new cell type are turned on. The genetic material in differentiated cells is complete, and can be used to clone an entire animal. Stem cells have a remarkable ability to repair DNA damage and prevent it from spreading to other cells. However, DNA damage can still occur over time. Stem cell therapies are being developed to treat a variety of medical conditions, including heart failure, spinal cord injuries, and diabetes. In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type. In mammals, roughly 50 to 150 cells make up the inner cell mass during the blastocyst stage of embryonic development, around days 5–14. These have stem-cell capability. In vivo, they eventually differentiate into all of the body's cell types (making them pluripotent). This process starts with the differentiation into the three germ layers – the ectoderm, mesoderm and endoderm – at the gastrulation stage. However, when they are isolated and cultured in vitro, they can be kept in the stem-cell stage and are known as embryonic stem cells (ESCs). Adult stem cells are found in a few select locations in the body, known as niches, such as those in the bone marrow or gonads. They exist to replenish rapidly lost cell types and are multipotent or unipotent, meaning they only differentiate into a few cell types or one type of cell. In mammals, they include, among others, hematopoietic stem cells, which replenish blood and immune cells, basal cells, which maintain the skin epithelium, and mesenchymal stem cells, which maintain bone, cartilage, muscle and fat cells. Adult stem cells are a small minority of cells; they are vastly outnumbered by the progenitor cells and terminally differentiated cells that they differentiate into. Research into stem cells grew out of findings by Canadian biologists Ernest McCulloch, James Till and Andrew J. Becker at the University of Toronto and the Ontario Cancer Institute in the 1960s. As of 2016, the only established medical therapy using stem cells is hematopoietic stem cell transplantation, first performed in 1958 by French oncologist Georges Mathé. Since 1998 however, it has been possible to culture and differentiate human embryonic stem cells (in stem-cell lines). The process of isolating these cells has been controversial, because it typically results in the destruction of the embryo. Sources for isolating ESCs have been restricted in some European countries and Canada, but others such as the UK and China have promoted the research. Somatic cell nuclear transfer is a cloning method that can be used to create a cloned embryo for the use of its embryonic stem cells in stem cell therapy. In 2006, a Japanese team led by Shinya Yamanaka discovered a method to convert mature body cells back into stem cells. These were termed induced pluripotent stem cells (iPSCs). In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type. In mammals, roughly 50 to 150 cells make up the inner cell mass during the blastocyst stage of embryonic development, around days 5–14. These have stem-cell capability. In vivo, they eventually differentiate into all of the body's cell types (making them pluripotent). This process starts with the differentiation into the three germ layers – the ectoderm, mesoderm and endoderm – at the gastrulation stage. However, when they are isolated and cultured in vitro, they can be kept in the stem-cell stage and are known as embryonic stem cells (ESCs). Adult stem cells are found in a few select locations in the body, known as niches, such as those in the bone marrow or gonads. They exist to replenish rapidly lost cell types and are multipotent or unipotent, meaning they only differentiate into a few cell types or one type of cell. In mammals, they include, among others, hematopoietic stem cells, which replenish blood and immune cells, basal cells, which maintain the skin epithelium, and mesenchymal stem cells, which maintain bone, cartilage, muscle and fat cells. Adult stem cells are a small minority of cells; they are vastly outnumbered by the progenitor cells and terminally differentiated cells that they differentiate into. Research into stem cells grew out of findings by Canadian biologists Ernest McCulloch, James Till and Andrew J. Becker at the University of Toronto and the Ontario Cancer Institute in the 1960s. As of 2016, the only established medical therapy using stem cells is hematopoietic stem cell transplantation, first performed in 1958 by French oncologist Georges Mathé. Since 1998 however, it has been possible to culture and differentiate human embryonic stem cells (in stem-cell lines). The process of isolating these cells has been controversial, because it typically results in the destruction of the embryo. Sources for isolating ESCs have been restricted in some European countries and Canada, but others such as the UK and China have promoted the research. Somatic cell nuclear transfer is a cloning method that can be used to create a cloned embryo for the use of its embryonic stem cells in stem cell therapy. In 2006, a Japanese team led by Shinya Yamanaka discovered a method to convert mature body cells back into stem cells. These were termed induced pluripotent stem cells (iPSCs) without stem cells you would only live for an hour because cells wouldn't be able to repair stem cells come from bone so consume gastroliths for healthy stem cells stem cell development and minerals which are critical for stem cell development, influencing their proliferation, differentiation, and overall function. This impact rely on the type of stem cell, the concentration of the mineral, and the presence of other cellular signals. Several key minerals have been identified to play specific roles in stem cell development. Calcium (\(Ca^{2+}\)) and phosphate (\(PO_{4}^{3-}\)) Osteogenesis: Calcium phosphate is a well-known inducer of osteogenesis, the differentiation of mesenchymal stem cells (MSCs) into bone-forming cells. Biomaterials made with calcium phosphate can promote bone healing by providing an osteoinductive environment for stem cells. Maintenance of pluripotency: A low concentration of intracellular calcium is often associated with maintaining the undifferentiated, or "stem cell," state in some type of stem cells, such as those in the skin and blood. Mechanisms: Calcium act as a secondary messenger that affect a wide range of cellular processes, including gene transcription, epigenetic regulation, and metabolism. Magnesium (\(Mg^{2+}\)) Bone and tissue repair: Magnesium is a crucial component in bone health and is being used in biomaterials to improve bone regeneration. Nervous system: Magnesium promote the proliferation and differentiation of neural stem cells (NSCs). Studies have shown it can enhance differentiation into neurons over glial cells, with implications for treating neurological disorders. Balance with calcium: The balance between magnesium and calcium is important. In some contexts, magnesium deficiency may accelerate differentiation, while sufficient level are necessary for proper function. Signaling: Magnesium ions influence metabolic and signaling pathways, such as the p38 signaling pathway, that guide stem cell development. Iron (\(Fe^{2+}\)/\(Fe^{3+}\)) and copper (\(Cu^{+}\)/\(Cu^{2+}\)) Essential metals: Iron and copper are essential for embryonic development and play crucial roles in metabolism, energy production, and oxygen transport. Redox state: As transition metals, iron and copper can easily switch oxidation states, making them key players in redox reactions and energy metabolism, which are fundamental to stem cell activity. Hematopoiesis: Iron in heme are critical for hematopoietic stem cells (HSCs), influencing their self-renewal and differentiation into red blood cells. Iron levels also interact with the immune system to regulate HSC development .Interaction: Copper and iron metabolism are interconnected. Copper deficiency can lead to iron transport problems, while excessive iron can interfere with copper absorption. Zinc Zn2 and manganese Mn2 Neurogenesis: Zinc promotes the proliferation of adipose-derived mesenchymal stem cells (AD-MSCs) and their differentiation toward a neuronal development. Manganese is required for the activation of the innate immune system and promote maturation of dendritic cells. Epigenetics: Zinc is essential for the function of many epigenetic enzymes and transcription factors, which regulate the expression of genes that control cell proliferation and differentiation. Immune response: Both zinc and manganese are involved in activating the cGAS-STING signaling pathway, which is part of the innate immune response and can influence anti-cancer immunity. Mitochondrial function: Zinc & Manganese are crucial minerals for mitochondrial metabolism and antioxidant defense system. An imbalance can lead to mitochondrial dysfunction and apoptosis.  The overall nutritional status of the organism are influenced by the effectiveness of minerals in promoting stem cell health. Signaling pathways: Minerals modulate key signaling pathways, such as ERK, p38, and Wnt, which direct stem cell development . Trees and other plants have specialized stem cells located in tissues called meristems, which drive their growth and regenerative capabilities. These undifferentiated cells allow for continuous, indeterminate growth throughout a tree's life, explaining how some can live for thousands of years. Changing people's lives, one stem cell at a time. Plant stem cells are found in distinct regions of a tree, called meristems, where they are organized to perform specific function. Apical Meristems: Located at the tips of shoots (Shoot Apical Meristem or SAM) and roots (Root Apical Meristem or RAM), these stem cells are responsible for a tree's primary growth—increasing its height and root length. Lateral Meristems: These cylindrical sheaths of stem cells run along the length of roots and shoots and cause secondary growth—an increase in a tree's girth or thickness. Lateral meristems include: Vascular Cambium: A thin layer of cells located between the wood (xylem) and the inner bark (phloem). These stem cells divide to produce secondary xylem inwards (forming wood) and secondary phloem outwards (forming bark). Cork Cambium: Produces the cork and bark that protect the tree's outer layer. Quiescent Center (QC): Found in the root apical meristem, this small group of slowly dividing cells act as a reservoir of stem cells. The QC is highly resistant to stress and can replace damaged stem cells, contributing to the tree's longevity. Plant vs. animal stem cells While both plant and animal stem cells are undifferentiated and capable of self-renewal, there are key differences in their nature and function. Plant Stem Cells Growth Period active throughout the plant's life, enabling indeterminate growth. Animal Stem Cells active mainly during embryonic development; adult stem cells have a more limited role in tissue repair. Potency many plant cells are totipotent, meaning a single cell can regenerate an entire organism. Embryonic stem cells are pluripotent (able to become most cell types), while adult stem cells are multipotent (can only become a few, related cell types). Control Primarily governed by positional information, meaning a cell's fate is dictated by its location relative to neighboring cells. Dependent on both local signals from a "stem cell niche" and fixed cell lineages. Reprogramming Differentiated cells can be easily reprogrammed to revert to a stem-cell-like state, a process exploited in tissue culture. Reprogramming differentiated cells (to create induced pluripotent stem cells or iPSCs) is a delicate and complex process. Emerging applications and research The remarkable properties of tree and other plant stem cells are being explored for numerous applications. Forestry and climate science: Scientists are using computer models to understand how cambium stem cells produce wood. This research could lead to faster-growing trees for a more sustainable timber industry and enhanced carbon capture. Lab-grown wood: Biologists have succeeded in growing wood-like material from plant stem cells in a lab. This technology, if perfected, could provide a sustainable alternative to traditional timber. Cosmetics and health: Stem cell extracts from plants like Swiss apples and lilacs are used in cosmetic products for their antioxidant and anti-inflammatory properties, though these products contain extracts, not live stem cells. Sustainable compounds: Culturing cambial meristematic cells (CMCs) provides a consistent source of valuable natural compounds, such as paclitaxel, which is used in medicine. Without stem cells you would only live for half an hour Stem cells are important because we need to replace our blood cells quickly and often, which we cannot do without stem cells. We all need lots of healthy blood cells to survive. People usually die when their bones stop making stem cells in nomine Patris et FiLii et Spiritus Sancti peace be still
https://www.youtube.com/watch?v=wQRUqeM-NZE&t=24s
Stem Cell Revolutions
https://www.youtube.com/watch?v=BsbQuXxP_O4
A Closer Look at...Stem Cells and Human Longevity
https://www.youtube.com/watch?v=W5o743HTUug
The Truth About Stem Cells
https://www.youtube.com/watch?v=62FdhX-zS2Y
23. Stem Cells

Steptomycin it is written in the Holy King James Bible the word of the Lord according to saint Moses the prophet of israel 1450 BC Before Christ Genesis 1:29 & God said, Behold, I have given you every herb bearing seed, which is upon the face of all the earth, & every tree, in the which is the fruit of a tree yielding seed; to you it shall be for meat. amen Streptomycin is an antibiotic medication used to treat a number of bacterial infections, including tuberculosis, Mycobacterium avium complex, endocarditis, brucellosis, Burkholderia infection, plague, tularemia, and rat bite fever. For active tuberculosis it is often given together with isoniazid, rifampicin, and pyrazinamide. It is administered by injection into a vein or muscle. Common side effects include vertigo, vomiting, numbness of the face, fever, and rash. Use during pregnancy may result in permanent deafness in the developing baby. Use appears to be safe while breastfeeding. It is not recommended in people with myasthenia gravis or other neuromuscular disorders. Streptomycin is an aminoglycoside. It works by blocking the ability of 30S ribosomal subunits to make proteins, which results in bacterial death. Albert Schatz first isolated streptomycin in 1943 from Streptomyces griseus. It is on the World Health Organization's List of Essential Medicines. The World Health Organization classifies it as critically important for human medicine it is written in the Holy King James Bible the revelation of saint John the apostle 50 AD Anno Domini in the year of our Lord Jesus Christ Revelation 22:2 In the midst of the street of it, & on either side of the river, was there the tree of life, which bare twelve manner of fruits, & yielded her fruit every month: & the leaves of the tree were for the healing of the nations. amen
https://www.youtube.com/watch?v=QZP5HQulZP0
Rutgers and Streptomycin: First Tuberculosis Treatment
https://www.youtube.com/watch?v=lBKuLLZ2aSo
Streptomycin: The Controversy over the First Tuberculosis Antibiotic (Schatz vs Waksman)

Strontium behaves very much like calcium. A large portion of the strontium will accumulate in bone. In adults, strontium mostly attaches to the surfaces of bones. In children, whose bones are still growing, strontium may be used by the body to create the hard bone mineral itself. People use strontium for tooth sensitivity, cancer that has spread to the bones, osteoporosis, osteoarthritis, and prostate cancer. It is also used for dental cavities, fractures, and other conditions, there is good scientific evidence to support these other uses. i thank Jesus Christ for the people who develop strontium supplements seeing how strontium heals the body may such scientists be blessed with the salvation health & longevity of Abraham our father i pray in the name of the Father Son & Holy Ghost ~ Strontium is what roman gladiators would take after fights to heal deep wounds modern humans have forsaken strontium not enough Americans take strontium 

Sulforaphane C6H11NOS2 blocks one of the cancerous stem cell pathways . A family of cruciferous vegetables called brassicas, also known as cole crops, provide a ton of health-boosting benefits it is written in the Holy King James Bible the revelation of the Lord according to saint John the apostle 50 AD Anno Domini in the year of our Lord Jesus Christ Revelation 22:2 In the midst of the street of it, & on either side of the river, was there the tree of life, which bare twelve manner of fruits, & yielded her fruit every month: & the leaves of the tree were for the healing of the nations. amen Brassicas are some of the stockiest, crunchiest plants you can find in the grocery store & include cabbage, collard greens, kale, cauliflower, broccoli, & Brussels sprouts. They're great for improving circulation & blood flow & can help prevent a number of age-related diseases. Scientists believe that broccoli & other brassicas contain sulfur-based chemicals called glucosinolates, which give these veggies their bitter flavor. When we chop, chew, & digest cruciferous veggies, these potent chemicals break down into bioactive compounds that may help prevent some forms of cancer. “Let food be thy medicine, and let medicine be thy food.” Hippocrates 460BC Let supplements be thy medicine & let medicine be thy supplement it is written in the Holy King James Bible the word of the Lord according to saint Moses the prophet of israel 1450 BC Before Christ Genesis 1:29 & God said, Behold, I have given you every herb bearing seed, which is upon the face of all the earth, & every tree, in the which is the fruit of a tree yielding seed; to you it shall be for meat. amen Sulforaphane detox microplastic Sulforaphane is a chemical that is made when chewing cruciferous vegetables such as broccoli, cauliflower, and broccoli sprouts. A chemical in these vegetables called glucoraphanin mixes with an enzyme in humans called myrosinase, which produces sulforaphane. Sulforaphane activate NRF2 gene which cells produce more antioxidant enzymes repair systems autophagy, lisosomal exocytosis open up lisosomes and dump the content out the cell 
https://www.youtube.com/watch?v=-I_quKMcD1M&t=2753s
Cancer Stem Cells: Are We Targeting the Right Cells?
https://www.youtube.com/watch?v=Q0lBVCpq8jc
Jed Fahey, Sc.D. on Isothiocyanates, the Nrf2 Pathway, Moringa & Sulforaphane Supplementation
https://www.youtube.com/watch?v=JZaJTkGcDeM
We Finally Know How To Detox Microplastics From Our Cells
https://www.youtube.com/watch?v=zz4YVJ4aRfg
Sulforaphane and Its Effects on Cancer, Mortality, Aging, Brain and Behavior, Heart Disease & More

Sulfur ancient Babylon knew sulfur as brimstone (American spelling & the preferred IUPAC name) is a chemical element; Sulfur has symbol S & atomic number 16. Sulfur is abundant, multivalent & nonmetallic. Under normal condition, sulfur atoms form cyclic octatomic molecules with the chemical formula S8 called octasulfur. Elemental sulfur is a bright yellow, crystalline solid at room temperature. Sulfur is the tenth most abundant element by mass in the universe & the fifth most common on Earth. Though sometimes found in pure, native form, sulfur on Earth usually occur as sulfide & sulfate mineral. Being abundant in native form, sulfur was known as brimstone in ancient time, being mentioned for its uses in the Hly King James Bible , ancient India, ancient Greece, China & ancient Egypt. Historically & in literature sulfur is also called brimstone, which means "burning stone". Almost all elemental sulfur is produced as a byproduct of removing sulfur-containing contaminants from natural gas & petroleum. The greatest commercial use of the element is the production of sulfuric acid for sulfate & phosphate fertilizers & other chemical processes. Sulfur is used in matches, insecticides & fungicides. Many sulfur compounds are odoriferous & the smell of odorized natural gas, skunk scent, bad breath, grapefruit or garlic are due to organosulfur compounds. Hydrogen sulfide gives the characteristic odor to rotting eggs & other biological processes. it is written in the Holy King James Bible the revelation of the Lord according to saint John the jewish apostle 50 AD Anno Domini in the year of our Lord Jesus Christ Revelation 22:2 In the midst of the street of it, & on either side of the river, was there the tree of life, which bare twelve manner of fruits, & yielded her fruit every month: & the leaves of the tree were for the healing of the nations. amen Sulfur is an essential element for all life, almost always in the form of organosulfur compounds or metal sulfides. Amino acids (two proteinogenic: cysteine & methionine & many other non-coded: cystine, taurine, etc.) & two vitamins (biotin & thiamine) are organosulfur compounds crucial for life. Cystine & cysteine are both amino acids, but cystine is the oxidized, stable dimer of two cysteine molecules. Cysteine has a reactive sulfhydryl group, while cystine has a disulfide bond that links the two cysteine units, making it more stable but less reactive. The body can easily convert cystine to cysteine through reduction to utilize cysteine for protein synthesis. Many cofactors also contain sulfur, including glutathione & iron–sulfur proteins. Disulfides, S–S bonds, confer mechanical strength & insolubility of protein keratin  (among others) , found in outer skin, hair & feathers. Sulfur is one of the core chemical elements needed for biochemical function & is an elemental macronutrient for all living organisms. Sulfur is an essential mineral with a wide array of benefit for the human body. It's crucial for building & repairing DNA, metabolizing food & maintaining the health of skin, hair & nails. Sulfur is also involved in the formation of collagen & the antioxidant glutathione, & greatly play a role in reducing inflammation to support joint health. “Let food be thy medicine, and let medicine be thy food.” Hippocrates 460BC Let supplements be thy medicine & let medicine be thy supplement take amazon.com sulfur pellets as of of your supplement it is written in the Holy King James Bible the word of the Lord according to saint Moses the jewish prophet of israel 1450 BC Before Christ Genesis 1:29 & God said, Behold, I have given you every herb bearing seed, which is upon the face of all the earth, & every tree, in the which is the fruit of a tree yielding seed; to you it shall be for meat. amen DNA Repair & Cell Protection: Sulfur is vital for building & repairing DNA, which is crucial for cell health & protection against cellular damage which cause cancer. Metabolism & Antioxidant Production: sulfur help the body metabolize food & is a component of glutathione, a powerful antioxidant that protect cells from damage. Connective Tissue Health: Sulfur is a key component of collagen, a protein that support the structure of skin, tendons, and ligaments (a ligament is a short band of tough, flexible fibrous connective tissue which connects two bones or cartilages or holds together a joint ) Joint Health: Many studies suggest sulfur, particularly in the form of MSM & sulfur pellets , reduce inflammation & pain associated with osteoarthritis. Immune Function: Sulfur play a role in supporting immune function & help the body fight off infection. Sulfate play a dual role in the immune system, acting as both a promoter & an inhibitor of immune responses through its presence in molecules like sulfated polysaccharides & sulfur-containing compounds. For instance, heparan sulfate & other sulfated polysaccharides regulate immune cell migration, cytokine activity & even initiate an immune response, a Cytokine is any of a number of substances, such as interferon, interleukin & growth factors, which are secreted by certain cells of the immune system & have an effect on other cells. While certain sulfates can suppress inflammation by modulating signaling pathways. The impact of sulfate on the immune system is great & complex & depend on the specific sulfur molecule for its function. How sulfate influence the immune system Regulation of immune cell function: Sulfated polysaccharides activate signaling pathways in immune cells like macrophages, T cells & natural killer (NK) cells, influencing their metabolism & function. Sulfates act as antioxidants & modulate immune response through mechanism like receptor binding & signaling. Modulation of inflammation: Sulfated polysaccharides inhibit inflammatory response by blocking inflammatory signal transduction & suppressing the activation of the complement system. Many studies show sulfates help reduce inflammation in disease like osteoarthritis by decreasing the production of pro-inflammatory cytokines such as TNF-α & IL-1β. Immune cell migration: Heparan sulfate help regulate leukocyte (white blood cells) migration by binding chemokines to the endothelium, which guide immune cells to sites of inflammation. Conversely, some sulfate compounds can block lymphocyte migration. Initiation of immune response: Interaction between immune cells & certain sulfated polysaccharides, such as those produced by bacteria like Desulfovibrio, Bilophila, Desulfomicrobium, and Fusobacterium, initiate a positive immune response. Role of sulfate-reducing bacteria: Sulfate-reducing bacteria in the gut microbiota influence immune response, anaerobic microorganisms that conduct dissimilatory sulfate reduction to obtain energy, resulting in the release of a great quantity of sulfide. Sulfate-reducing bacteria are commonly isolated from environmental sources, but are also present in the digestive tract of animals & humans. SRBs are anaerobic and use sulfate for energy, producing hydrogen sulfide H2S as a byproduct. Small amounts of H2S is beneficial. Other roles: Sulfur amino acids are vital for immune function & antioxidant defense. Some sulfated compounds, like dextran sulfate, modulate the number of regulatory T cells, which is crucial for maintaining immune tolerance & preventing autoimmune disease. Skin acne treatment: Sulfur is a common ingredient in acne treatment due to its ability to kill bad bacteria, reduce sebum (oil) production & exfoliate dead skin cells. Anti-inflammatory: Sulfur reduce inflammation & redness associated with skin condition like acne, eczema & rosacea. Exfoliation: Sulfur soften & exfoliate thick, dead skin, which improve the appearance of skin & promote a healthy complexion. Keratin Production: Sulfur is a component of keratin, a protein that is essential for the structure of skin, hair & nails. Other benefit: Blood Sugar Regulation: Sulfur, as a component of insulin, needed to regulate blood sugar level. Cardiovascular Health: Many research prove sulfur compounds have a role in vasodilation reducing blood pressure. Detoxification: Traditionally, sulfur has been used to help detoxify the body to draw out infection. Where to find sulfur: Sulfur is naturally present in small amount Portland concrete cement but best are sulfur pellets important note it is written in the Holy King James Bible the word of the Lord according to saint Moses the jewish prophet of israel 1450 BC Before Christ Genesis 19:21-27 & the angel said unto Lot, See, I have accepted thee concerning this thing also, that I will not overthrow this city, for the which thou hast spoken. 22 Haste thee, escape thither; for I cannot do any thing till thou be come thither. Therefore the name of the city was called Zoar. 23 The sun was risen upon the earth when Lot entered into Zoar. 24 Then the LORD rained upon Sodom & upon Gomorrah brimstone & fire from the LORD out of heaven; 25 & the LORD overthrew those cities & all the plain & all the inhabitants of the cities & that which grew upon the ground. 26 But Lot's wife looked back from behind Lot & she became a pillar of salt. 27 & Abraham gat up early in the morning to the place where Abraham stood before the LORD: amen the ancient biblical Hebrew patriarch father Abraham lived to be 175 years old father Abraham knew everything about the periodic table of father Abraham time sulfur was called brimstone which means "burning stone" in ancient day & father Abraham ingested his daily dose of sulfur gastroliths , saints who want to live as long as father Abraham must daily take their sulfur pellet supplement . The amino acids methionine & cysteine are the two primary amino acids that contain sulfur. While other sulfur-containing amino acids like homocysteine & taurine exist, methionine & cysteine are the only two incorporated into proteins. Methionine: An essential amino acid, meaning the body cannot produce it & must be obtained from sulfur pellet supplement. Methionine play a crucial role in protein synthesis & various metabolic processes. Cysteine: Can be synthesized by the body from methionine. Cysteine a key component of many proteins is involved in detoxification & antioxidant function. Homocysteine: An intermediate in the metabolism of methionine. Homocysteine is not a standard proteinogenic amino acid but play a role in methylation & other metabolic pathway. Taurine: Another sulfur-containing amino acid, abundant in animal tissue, used in RNA transfer into protein. You have no idea just how important sulfur is without sulfur RNA transfer is compromised because Taurine the sulfur-containing amino acid cannot function, abundant in animal tissue, sulfur is used by moose & deer, primarily to deter ticks & as a mineral supplement, with the scent also attracting moose & deer to mineral sites. Essential Nutrient: Sulfur is a necessary mineral for animals, playing a role in the formation of amino acids, vitamins, and other vital nutrients. Impact on Hair & Hooves: Sulfur is a component of some amino acids & is important for healthy hair, hoof & horn development. Supplements containing sulfur include Methylsulfonylmethane (MSM) & amazon.com sulfur pellets , which are popular choice for joint pain, inflammation & overall health. Sulfur is also a component of the vitamins Biotin (B7) and Thiamine (B1), these are essential often taken along with vital sulfur supplements. Other sulfur-containing supplements are Glucosamine Sulfate and Chondroitin Sulfate, often combined with MSM for joint health. Creatine itself does not contain sulfur; however, one of the amino acids used to synthesize creatine in the body L-methionine, is a sulfur-containing amino acid. Sulfur a component of many amino acids & proteins, but the chemical structure of creatine does not include a sulfur atom. Creatine a metabolite of three amino acids: L-arginine, Glycine, and L-methionine be blessed take your sulfur pellet supplement . Therapeutic use & benefit Magnesium sulfate MgSO4: is a medical treatment used for certain heart condition can act as an antiarrhythmic agent, particularly for ventricular arrhythmias. Ventricular arrhythmia is an abnormal heart rhythm originating in the heart's lower chambers (ventricles), causing the heart to beat too fast, too slow, or irregularly. This condition, such as ventricular tachycardia (a fast rhythm) and ventricular fibrillation (a chaotic, uncoordinated rhythm), is life-threatening by preventing the heart from pumping enough blood. Symptoms include dizziness, palpitations, shortness of breath, or fainting, and emergency treatment may involve CPR and defibrillation for the most severe cases. Sulfur stabilize cardiac repolarization in many heart failure patients. Sulfur can attenuate blood pressure by decreasing the vascular response to certain substances. Chondroitin sulfate is essential for the formation of heart valves, you have no clue how important sulfur is in the human body , with out sulfur your heart valves die which lead to a heart attack , according to a publication of the National Institutes of Health (NIH) . Sulfate moieties in the extracellular matrix (ECM) are crucial for extra cellular matrix function, acting as binding sites for growth factors & other molecules, playing roles in cell signaling, proliferation & tissue structure. Different type of sulfated molecules, like chondroitin sulfate & heparan sulfate, are found in the ECM & have specific role in tissue integrity & cell behavior. Alteration in ECM sulfation can negatively influence cell response to growth factors, while enzymes like heparanase modify the ECM by cleaving sulfated chains, affecting processes like cancer metastasis and immune cell infiltration. Key function of sulfate in the ECM Growth factor binding: Sulfate groups, particularly on heparan sulfate proteoglycans (HSPGs), are essential for binding & modulating growth factors like fibroblast growth factors (FGFs). A fibroblast is a type of cell that build and maintain connective tissue by producing extracellular matrix component like collagen & elastin. fibroblasts are the most common cells in connective tissue, providing a structural framework for organs & play a key role in wound healing by migrating to damage sites to repair tissue. Cell proliferation: Interaction between sulfated ECM molecules & growth factors stimulate cell proliferation. Structural integrity: Sulfated proteoglycans, such as those found in perineuronal nets (PNNs), are key components of the ECM that contribute to its structural & functional integrity. Perineuronal nets (PNNs) are specialized, dense, lattice-like structure of the extracellular matrix (ECM) that surround the cell body & proximal dendrites of certain neurons in the central nervous system (CNS), particularly parvalbumin-expressing (PV+) inhibitory interneurons. Perineuronal nets play a crucial role in regulating brain function & plasticity in adulthood. Regulation of Synaptic Plasticity: PNN Perineuronal nets form during development around the time that critical periods of heightened neuroplasticity end, essentially "locking in" mature neural circuits & preventing excessive rewiring. Perineuronal nets removal in adult animals can "reopen" juvenile-like plasticity, Modulation of Neuronal Excitability: Perineuronal nets help maintain the appropriate balance of excitation & inhibition in brain circuits & are important for generating & maintaining brain oscillation, such as gamma waves, which are involved in cognitive process like learning & memory. Memory Formation & Retention: Perineuronal nets are dynamically modulated during learning & memory formation. Perineuronal nets are critical for consolidating long-term memories & making fear memories resistant to erasure (extinction). Sulfur is vital to say the least important for proper brain function Example of sulfate-ECM interaction FGF modulation: Decreased sulfation of the ECM can actually upregulate the response of certain cells to heparin-binding growth factors. Consequences of decreased biological sulfation: Nervous system disorders: Lower sulfation activity has been linked to the development of certain nervous system disorders. Impaired detoxification: Sulfation is one pathway the body use to eliminate toxic compounds & certain drugs (like acetaminophen), so reduced capacity can affect this process. Neuroprotection issue: Reduced sulfation of certain molecules can exacerbate oxidative stress, which may contribute to neurodegenerative disease. Disease states: Decreased sulfation of specific proteins & other molecules has been observed in condition such as diabetes, gastric ulcers, and primary sclerosing cholangitis ( Sclerosing cholangitis is a chronic liver disease that cause inflammation & scarring of the bile ducts, leading to their narrowing or blockage. This buildup of bile cause liver damage & lead to complication like cirrhosis & liver failure over time. Symptoms include fatigue, itching, jaundice & abdominal pain, though many people are initially asymptomatic & are diagnosed after routine blood tests show abnormal liver function ) . Skeletal/connective tissue problems: Reduced sulfation of chondroitin sulfate & heparan sulfate in cartilage & other tissue negatively affect their structure & function. Cancer metastasis: Heparan sulfate is involved in the metastatic process, with its abundance & modification by enzymes influencing tumor cell movement & the elimination of new tumors. Autistic kids have 1/3 sulfate in the blood compared to normal kids . Decreased sulfation pathologies Associated Condition &Effect: Nervous system disorder. Reduced sulfation of chondroitin sulfate cause cancer. Impaired elimination of toxic compounds. Association with chronic fatigue & reduced quality of life in patients with PSC Primary Sclerosing Cholangitis . Enhanced vulnerability to oxidative stress & associated neuronal cell death in studies with induced sulfation inhibitors. Immune cell infiltration: Enzymes called heparanases can degrade the heparan sulfate in the subendothelial ECM, which is thought to facilitate the invasion of immune cells, such as neutrophils, into tissue. Heparan sulfate (HS) is a linear polysaccharide found on all cell surfaces & in the extracellular matrix, acting as a core component of proteoglycans . Proteoglycans are macromolecules consisting of a core protein to which one or more sugar chains, called glycosaminoglycans (GAGs), are covalently attached. Proteoglycans are crucial component of the extracellular matrix (ECM) & all cell surfaces, where they play diverse roles including providing structural support, regulating mechanical properties & controlling the bioavailability of growth factors. Proteoglycans support tissue hydration, resilience & repair & Proteoglycans dysfunction lead to disease. Heparan sulfate play a crucial role in regulating a wide range of biological function, including cell signaling, development & immune response, by interacting with various proteins & growth factors. Because of its involvement in these fundamental process, heparan sulfate is essential for maintaining homeostasis, but its dysregulation is linked to diseases like cancer and genetic disorders such as Sanfilippo syndrome. heparan sulfate is present in all mammalian tissue throughout multicellular organisms, from simple invertebrates to humans. Neural plasticity: In the brain, chondroitin sulfate proteoglycans (CSPGs) are integral to structure like Perineuronal nets, which regulate synaptic plasticity & influence development process. Therapeutic & research application Osteoarthritis: Chondroitin sulfate & hyaluronic acid are being studied for their potential to alleviate ECM degradation in osteoarthritis. Bone generation: Dextran sulfate has been used in combination with other component to enhance ECM deposition to promote osteogenic differentiation in bone regeneration. Sulfate is an essential anion for numerous bodily function, including cell growth, specially detoxification & the development of structural molecules like glycosaminoglycans & proteoglycans. Sulfate is crucial for "sulfonation," a process that modifies steroids, proteins, hormones & other compounds to regulate their function & solubility. Sulfur is critical internally. Enzymes called sulfotransferases attach sulfate to other molecules, a process vital for modifying the activity of steroids, neurotransmitters & other compounds. Sulfotransferases are enzymes that transfer a sulfate group from a donor, like the cofactor 3'-phosphoadenosine-5'-phosphosulfate (PAPS), to an acceptor molecule such as an alcohol or amine. This process, known as sulfation or sulfuryl transfer, play a crucial role in various biological processes, including hormone regulation, cell communication & the metabolism of drugs & xenobiotics. Sulfotransferases are found in both the cytoplasm & cell membrane & can sulfate either small molecules (like steroids & drugs) or large molecules (like proteins & glycosaminoglycans).  Function of sulfotransferases Drug metabolism: Sulfotransferases are key "Phase II" drug-metabolizing enzymes, often making drugs more water-soluble for easier excretion. Hormone & neurotransmitter regulation: For neurotransmitters like dopamine, sulfation by specific sulfotransferases (e.g., SULT1A3 Sulfotransferase family 1A member 3 ) converts the active molecule dopamine into an inactive sulfate conjugate (dopamine sulfate) which is then more readily eliminated from the body, thereby regulating neurotransmission preventing potential neurotoxicity. There is an entire gene specially created for the purpose of processing sulfur in the human body (Sulfotransferase family 1A member 3) a human gene that encodes an enzyme (protein) primarily responsible for the sulfate conjugation of monoamine neurotransmitters such as dopamine, epinephrine, and norepinephrine. This process, called sulfation, is a crucial part of the body's mechanism for metabolizing and eliminating toxins. Cellular processes: Sulfotransferases are involved in cell communication, growth, development & defense. Bioactivation: In some cases, Sulfotransferases can bioactivate compounds. For example, minoxidil is converted to minoxidil sulfate by a sulfotransferase, which is the active form that promote hair growth. Detoxification: Sulfotransferases help detoxify the body by sulfating harmful compounds, such as many carcinogens, making them less toxic & easier to excrete. Cytosolic sulfotransferases: Found in the cytoplasm, these enzymes typically sulfate smaller molecules, including many therapeutic drugs, steroids & bioamines. Membrane-associated sulfotransferases: Located in the Golgi membrane, these enzymes sulfate larger molecules like proteins and proteoglycans (e.g., glycosaminoglycans). Genetic variation: Polymorphisms in sulfotransferase genes can lead to differences in enzyme activity between individuals, which affect their response to certain drugs or their risk for certain disease. Drug-drug interaction: Some drugs can inhibit sulfotransferases, potentially affecting the metabolism of other drugs that rely on sulfation. Structural integrity: Sulfate is a key component of structural molecules like hyaluronic acid , chondroitin sulfate & heparan sulfate, found in cartilage & other connective tissue. Sulfate is also part of mucus, which protect surfaces like the stomach lining. Development: Sulfate is essential for proper development, with fetal development relying on sulfate supplied by the mother. Detoxification: The liver uses sulfate to help break down & remove toxins & other foreign substances (xenobiotics). Cellular function: All cells require a steady supply of sulfate, which is transported into & out of cells via specific protein transporters so make sure to take MSM & amazon.com sulfur pellet supplement. Sulfate is the 8th most abundant element by weight, following potassium. The eleven most abundant elements in the human body by mass are: 1 Oxygen (approx. 65%) 2 Carbon (approx. 18%) 3 Hydrogen (approx. 10%) 4 Nitrogen (approx. 3%) 5 Calcium (approx. 1.4%) 6 Phosphorus (approx. 1%) 7 Potassium (approx. 0.25%) 8 Sulfur (approx. 0.25%) 9 Sodium (approx. 0.15%) 10 Chlorine (approx. 0.15%) & 11 Magnesium (approx. 0.005%) all these elements can be found in supplements so ake sure to supplement be blessed by God Almighty. Sulfur makes up approximately 0.2% to 0.25% of body mass, which is roughly 140 grams in a 70 kg person, Sulfate's primary role in blood cells is its presence in cholesterol sulfate, a membrane component that stabilizes blood cell membranes, especially red blood cells (erythrocytes) and platelets. Cholesterol sulfate protect red blood cells from osmotic lysis & support platelet adhesion & membrane function. Sulfate is also involved in other blood-related function, such as modulating clotting & acting as a key component of the endothelial glycocalyx that maintain vascular integrity.  Role in blood cells & vascular health Membrane stabilization: Cholesterol sulfate stabilize the membranes of red blood cells, protecting them from bursting (osmotic lysis) & helping red blood cells maintain their shape to flow smoothly through vessels. Platelet function: Cholesterol sulfate is present in platelet membrane & play a critical role in platelet adhesion, a key process in blood clotting. Signal transduction: Cholesterol sulfate can regulate the activity of enzymes like serine proteases (involved in blood clotting) & protein kinase C, which are crucial for signal transduction within cells. Vascular integrity: Extracellular sulfate is incorporated into sulfated glycosaminoglycans, which are components of the endothelial glycocalyx ( The glycocalyx is a protective layer of sugar-protein & sugar-lipid molecules that coat the surface of almost all cells. The glycocalyx function as a cellular "cloak" that play a critical role in cell-cell communication, adhesion & recognition. In blood vessels, the endothelial glycocalyx acts as a barrier, regulating vascular permeability, fluid exchange, blood flow & inflammation ). This layer is essential for maintaining the structural & functional integrity of blood vessels & regulating blood flow. Sulfonation: Inorganic sulfate is a fundamental nutrient that is used to sulfonate other molecules. Tyrosine sulfonation is a post-translational modification that occur on many proteins, including some that are involved in blood clotting. Other important role sulfate is an essential nutrient for overall physiological homeostasis, with its concentration in the body tightly regulated by specialized sulfate transporters. Sulfate is the fourth most abundant anion in human serum & is required for the sulfonation of many molecules, including proteoglycans, steroids & bile acids. The sulfonation process modifies the structure & function of these molecules & impaired sulfonation pathways the lack of sulfur supplement lead to serious health issues . Sulfate is linked to bone marrow through various mechanisms, primarily as a component of sulfated proteoglycans like heparan sulfate, which is essential for maintaining the bone marrow microenvironment & regulating blood cell production. Additionally, deficiencies in specific sulfatases impair bone marrow function . Heparan sulfate (HS) is a major component of the bone marrow's stromal cells, which are crucial for hematopoiesis (blood cell formation). Regulation of blood cell production: Heparan sulfate play a role in regulating the proliferation & development of hematopoietic stem & progenitor cells (HSPCs). Cell migration: Heparan sulfate is involved in regulating the migration of HSPCs, with some studies suggesting that an excess of it can inhibit migration by interfering with certain signaling pathways, like the one involving CXCL12 . Stem cell support: Heparan sulfate enhance the self-renewal & therapeutic potential of mesenchymal stem cells (MSCs) of bone marrow. Impact of sulfate-related deficiencies: A deficiency in sulfatase, which are enzymes that break down sulfate esters, lead to significant abnormalities in bone marrow hematopoiesis. Myeloid refers to cells & tissue related to bone marrow, particularly blood-forming cells like red blood cells, platelets & certain white blood cells (granulocytes & monocytes). These cells originate in the bone marrow & are crucial for immune defense & oxygen transport. Myeloid deficiency: A specific myeloid deficiency in heparan sulfate 6-O-endosulfatases enzymes can cause an expansion of the stem cell pool & arrest of red blood cell & platelet production, particularly in males, as shown in mouse models. Indoxyl sulfate: This uremic toxin, elevated in patients with chronic kidney disease, can inhibit osteogenesis (bone formation) in bone marrow mesenchymal stem cells. Indoxyl sulfate (also known as indican or 3-indoxyl sulfate) is a protein-bound uremic toxin derived from the breakdown of the dietary amino acid L-tryptophan by gut bacteria. It is normally cleared by the kidneys, but accumulates in patients with chronic kidney disease (CKD), where high level is associated with various toxic effect.  Other role of sulfates Chondroitin sulfate: This sulfated glycosaminoglycan has been shown to stimulate the production of hematopoietic cells in bone marrow cultures, suggesting it may also play a role in regulating hematopoiesis. Therapeutic potential: Altering the heparan sulfate in the bone marrow niche is being investigated as a potential target for stem cell therapy. Sulfate is connected to bone in two primary ways: as a component of calcium sulfate bone grafts used in orthopedic surgery & as a crucial element in heparan sulfate proteoglycans (HSPGs), which are involved in bone repair . Yes, sulfates play a key role in the body's natural detoxification processes, specifically through a major metabolic pathway called sulfation. How Sulfates Assist in Detoxification :The process of sulfation occur primarily in the liver (Phase II detoxification) and other tissue, where sulfate is conjugated (bound) with a variety of substances to facilitate their elimination from the body. Binding to Toxins: Sulfates act as natural cleansing agents by binding to harmful substances, essentially tagging them for removal through urine and bile. Metabolism of Harmful Substances: This pathway break down various compounds, including: drugs & food additives environmental toxins & contaminants steroid & thyroid hormones , dead Neurotransmitters & toxins produced from intestinal bacteria . Sulfates contribute to the production of glutathione, a powerful antioxidant essential for the liver's role in eliminating heavy metals, alcohol & other toxin. Important Consideration Dietary Sources: The body obtains sulfate from the diet as free inorganic sulfate , through the metabolism of sulfur-containing amino acids (like cysteine & methionine) & the best is to supplement with amazon.com sulfur pellets . Product Sulfates (Surfactants): The sulfates found in personal care products like shampoos and soaps (e.g., sodium lauryl sulfate, sodium laureth sulfate) are surfactants used for cleaning & creating lather. When absorbed through the skin, the small amounts that enter the bloodstream are quickly broken down & excreted & these do not accumulate in the body. Epsom Salt Baths: While some people use Epsom salt (magnesium sulfate) baths for "detox" benefits, there is sufficient scientific evidence to support the claim that this method removes toxins from the body. In summary, sulfate is a vital mineral that your body use internally as part of its sophisticated, natural detoxification system . Yes, sulfur, often in the form of sulfate compounds, is an essential element found in absolutely every cell of the human body just to let you know how importat sulfate is . Sulfate plays a critical role in numerous cellular & metabolic processes across all living organisms, from bacteria & plants to humans. Key Function of Sulfate in Cells Sulfate & various organosulfur compounds are integral to cell structure, function & signaling:  Structural Components: Sulfated molecules, such as heparan sulfate proteoglycans & cholesterol sulfate, are embedded within & attached to cell membranes & the extracellular matrix, influencing cell adhesion & structural integrity. Protein Synthesis: Sulfur-containing amino acids, primarily methionine & cysteine, are essential building blocks for all proteins. Methionine is crucial for initiating protein synthesis. Enzymes & Cofactors: Many critical enzymes & cofactors, including glutathione & iron-sulfur proteins, contain sulfur. Signaling & Regulation: Sulfated glycosaminoglycans modulate the actions of a large number of extracellular ligands, such as growth factors & chemokines (Chemokines are a family of small, secreted proteins that act as chemical signals to guide the movement of cells, especially immune cells like leukocytes. They attract white blood cells to areas of inflammation, infection, or disease & are crucial for the normal function of the immune system, as well as for processes like tissue patterning & wound healing. Their functions include recruiting immune cells to fight pathogens, organizing lymph nodes & decreasing cancer growth & spread ) In biology, a ligand is a molecule that binds to a receptor on a larger molecule, such as hormones binding to receptors or neurotransmitters binding to nerve cell channels, to produce a biological effect. Sulfur play a vital role in cell signaling & development. Vitamins & Hormones: Essential vitamins like biotin & thiamine (B1) & many hormones, are sulfur-containing compounds. Cells actively transport & regulate the concentration of sulfate to maintain cellular homeostasis due to its importance in many vital biological function seeing how many use the body has of sulfur it is dire therefore vital to supplement with amazon.com sulfur pellets which are just as vital for plant. Sulfates play a complex & vital role in the body's natural process of clearing triglycerides from the bloodstream. The direct impact of simply consuming sulfates on triglyceride level has mixed evidence, with some specific compounds showing promise in research study. Natural Mechanism the body uses sulfated molecules, specifically heparan sulfate proteoglycans found on liver cell surface, to clear triglyceride-rich lipoproteins (VLDL & chylomicrons) from the plasma. This process is a major clearance pathway & its efficiency is directly related to the degree of sulfation of these molecules. Genetic studies in both mice & humans support this: Mice with reduced liver heparan sulfate sulfation accumulate plasma triglycerides ,liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members. A specific genetic variant in the human SULF2 gene, affect heparan sulfate remodeling & is associated with lower fasting & postprandial triglyceride level. This indicates that healthy & appropriate sulfate function is crucial for normal lipid metabolism so make sure you take your sulfur pellet supplement of amazon.com to lower your triglycerides be blessed by God Almighty missa orationis peace be still in nomine Patris et FiLii et Spiritus Sancti amen
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Supplement take your vitamins & minerals so that you may live through hundreds & thousands of years by the grace of Jesus Christ & remember to fast be blessed by God Almighty missa orationis peace be still in nomine Patris et FiLii et Spiritus Sancti amen
Developed on Lenovo M800 Windows 10 Shot with Galaxy Ao4S edited with Davinci Resolve & Photoshop cs 26.10.0